Welcome to LookChem.com Sign In|Join Free

CAS

  • or

582308-33-6

Post Buying Request

582308-33-6 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

582308-33-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 582308-33-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,2,3,0 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 582308-33:
(8*5)+(7*8)+(6*2)+(5*3)+(4*0)+(3*8)+(2*3)+(1*3)=156
156 % 10 = 6
So 582308-33-6 is a valid CAS Registry Number.

582308-33-6Relevant articles and documents

P2 pyridine N-oxide thrombin inhibitors: A novel peptidomimetic scaffold

Nantermet, Philippe G.,Burgey, Christopher S.,Robinson, Kyle A.,Pellicore, Janetta M.,Newton, Christina L.,Deng, James Z.,Selnick, Harold G.,Lewis, S. Dale,Lucas, Bobby J.,Krueger, Julie A.,Miller-Stein, Cynthia,White, Rebecca B.,Wong, Bradley,McMasters, Daniel R.,Wallace, Audrey A.,Lynch Jr., Joseph J.,Yan, Youwei,Chen, Zhongguo,Kuo, Lawrence,Gardell, Stephen J.,Shafer, Jules A.,Vacca, Joseph P.,Lyle, Terry A.

, p. 2771 - 2775 (2007/10/03)

In this study, we have demonstrated that the critical hydrogen bonding motif of the established 3-aminopyrazinone thrombin inhibitors can be effectively mimicked by a 2-aminopyridine N-oxide. As this peptidomimetic core is more resistant toward oxidative metabolism, it also overcomes the metabolic liability associated with the pyrazinones. An optimization study of the P 1 benzylamide delivered the potent thrombin inhibitor 21 (K i = 3.2 nM, 2xaPTT = 360 nM), which exhibited good plasma levels and half-life after oral dosing in the dog (Cmax = 2.6 μM, t 1/2 = 4.5 h).

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 582308-33-6