583840-03-3 Usage
Chemical Properties
Pale Yellow Solid
Uses
A metabolite of Sorafenib, a potent Raf kinase inhibitor.
Check Digit Verification of cas no
The CAS Registry Mumber 583840-03-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,8,3,8,4 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 583840-03:
(8*5)+(7*8)+(6*3)+(5*8)+(4*4)+(3*0)+(2*0)+(1*3)=173
173 % 10 = 3
So 583840-03-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H16ClF3N4O4/c1-26-19(30)18-11-15(8-9-29(18)32)33-14-5-2-12(3-6-14)27-20(31)28-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,27,28,31)
583840-03-3Relevant articles and documents
Aryl ureas as kinase inhibitors
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Page/Page column 21, (2015/11/30)
This invention relates to new aryl ureas and methods for their synthesis. The inventive compounds are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VE
Aryl ureas as kinase inhibitors
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, (2008/06/13)
This invention relates to new aryl ureas and methods for their synthesis. The inventive compounds are useful in the treatment of (i) raf mediated diseases, for example, cancer, (ii) p38 mediated diseases such as inflammation and osteoporosis, and (iii) VEGF mediated diseases such as angiogenesis disorders.
