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584-04-3

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584-04-3 Usage

Purification Methods

Purify the dithiol as for 2,3-dimercapto-1-propanol above. [Johary & Owen J Chem Soc 1305 1955, Beilstein 1 IV 2773 or 2 IV 1102.]

Check Digit Verification of cas no

The CAS Registry Mumber 584-04-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,8 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 584-04:
(5*5)+(4*8)+(3*4)+(2*0)+(1*4)=73
73 % 10 = 3
So 584-04-3 is a valid CAS Registry Number.
InChI:InChI=1/C3H8OS2/c4-3(1-5)2-6/h3-6H,1-2H2

584-04-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-dimercaptopropan-2-ol

1.2 Other means of identification

Product number -
Other names 1,3-Dimercaptopropanol-2

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:584-04-3 SDS

584-04-3Relevant articles and documents

Total synthesis of gymnorrhizol, an unprecedented 15-membered macrocyclic polydisulfide from the Chinese mangrove bruguiera gymnorrhiza

Gong, Jing-Xu,Shen, Xu,Yao, Li-Gong,Jiang, Hualiang,Krohn, Karsten,Guo, Yue-Wei

, p. 1715 - 1716 (2007)

The total synthesis of gymnorrhizol, a naturally occurring macrocyclic polydisulfide with a new skeleton and a potent proteintyrosinephosphatase 1B inhibitor, was prepared in three steps, starting from (R)-1-bromo-3- chloroisopropanol and 1,3-dichloropropan-2-ol.

A small molecule probe reveals declined mitochondrial thioredoxin reductase activity in a Parkinson's disease model

Liu, Yaping,Ma, Huilong,Zhang, Liangwei,Cui, Yajing,Liu, Xiaoting,Fang, Jianguo

, p. 2296 - 2299 (2016)

The first off-on probe, Mito-TRFS, for imaging the mitochondrial thioredoxin reductase (TrxR2) in live cells was reported. In a cellular model of Parkinson's disease (PD), Mito-TRFS staining discloses a drastic decline of the TrxR2 activity, providing a mechanistic link of TrxR2 dysfunction to the etiology of PD.

Molecular rods based on oligo-spiro-thioketals

Wessig,Gerngro?,Freyse,Bruhns,Przezdziak,Schilde,Kelling

, p. 1125 - 1136 (2016/02/19)

We report on an extension of the previously established concept of oligospiroketal (OSK) rods by replacing a part or all ketal moieties by thioketals leading to oligospirothioketal (OSTK) rods. In this way, some crucial problems arising from the reversible formation of ketals are circumvented. Furthermore, the stability of the rods toward hydrolysis is considerably improved. To successfully implement this concept, we first developed a number of new oligothiol building blocks and improved the synthetic accessibility of known oligothiols, respectively. Another advantage of thioacetals is that terephthalaldehyde (TAA) sleeves, which are too flexible in the case of acetals can be used in OSTK rods. The viability of the OSTK approach was demonstrated by the successful preparation of some OSTK rods with a length of some nanometers.

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