Welcome to LookChem.com Sign In|Join Free

Cas Database

586-61-8

586-61-8

Identification

Synonyms:4-Isopropylbromobenzene;4-Isopropylphenyl bromide;NSC 97223;p-Bromocumene;p-Bromoisopropylbenzene;p-Isopropylbromobenzene;p-Isopropylphenyl bromide;Cumene,p-bromo- (6CI,7CI,8CI);1-Bromo-4-isopropylbenzene;2-(4-Bromophenyl)propane;2-(p-Bromophenyl)propane;4-Bromo-1-isopropylbenzene;4-Bromoisopropylbenzene;

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Pictogram(s):HarmfulXn; IrritantXi; DangerousN

  • Hazard Codes:Xn,N,Xi

  • Signal Word:Warning

  • Hazard Statement:H302 Harmful if swallowedH411 Toxic to aquatic life with long lasting effects

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:TRC
  • Product Description:1-Bromo-4-isopropylbenzene
  • Packaging:1g
  • Price:$ 55
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TRC
  • Product Description:1-Bromo-4-isopropylbenzene
  • Packaging:2.5g
  • Price:$ 65
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:4-Bromocumene
  • Packaging:25G
  • Price:$ 82
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TCI Chemical
  • Product Description:4-Bromocumene
  • Packaging:5G
  • Price:$ 21
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:4-Bromoisopropylbenzene 95%
  • Packaging:25g
  • Price:$ 36
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:4-Bromoisopropylbenzene 95%
  • Packaging:100g
  • Price:$ 112
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Frontier Specialty Chemicals
  • Product Description:4-Bromoisopropylbenzene 95%
  • Packaging:25g
  • Price:$ 288
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Frontier Specialty Chemicals
  • Product Description:4-Bromoisopropylbenzene 95%
  • Packaging:5g
  • Price:$ 88
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:1-Bromo-4-isopropylbenzene 98%
  • Packaging:100g
  • Price:$ 130
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Chemenu
  • Product Description:1-Bromo-4-isopropylbenzene 95+%
  • Packaging:500g
  • Price:$ 323
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 20 Articles be found

Cobalt-Catalyzed Hydrogenations via Olefin Cobaltate and Hydride Intermediates

Sandl, Sebastian,Maier, Thomas M.,Van Leest, Nicolaas P.,Kr?ncke, Susanne,Chakraborty, Uttam,Demeshko, Serhiy,Koszinowski, Konrad,De Bruin, Bas,Meyer, Franc,Bodensteiner, Michael,Herrmann, Carmen,Wolf, Robert,Von Jacobi Wangelin, Axel

, p. 7596 - 7606 (2019/08/20)

Redox noninnocent ligands are a promising tool to moderate electron transfer processes within base-metal catalysts. This report introduces bis(imino)acenaphthene (BIAN) cobaltate complexes as hydrogenation catalysts. Sterically hindered trisubstituted alkenes, imines, and quinolines underwent clean hydrogenation under mild conditions (2-10 bar, 20-80 °C) by use of the stable catalyst precursor [(DippBIAN)CoBr2] and the cocatalyst LiEt3BH. Mechanistic studies support a homogeneous catalysis pathway involving alkene and hydrido cobaltates as active catalyst species. Furthermore, considerable reaction acceleration by alkali cations and Lewis acids was observed. The dinuclear hydridocobaltate anion with bridging hydride ligands was isolated and fully characterized.

Amine-Borane Dehydrogenation and Transfer Hydrogenation Catalyzed by α-Diimine Cobaltates

Maier, Thomas M.,Sandl, Sebastian,Shenderovich, Ilya G.,Jacobi von Wangelin, Axel,Weigand, Jan J.,Wolf, Robert

supporting information, p. 238 - 245 (2019/01/04)

Anionic α-diimine cobalt complexes, such as [K(thf)1.5{(DippBIAN)Co(η4-cod)}] (1; Dipp=2,6-diisopropylphenyl, cod=1,5-cyclooctadiene), catalyze the dehydrogenation of several amine-boranes. Based on the excellent catalytic properties, an especially effective transfer hydrogenation protocol for challenging olefins, imines, and N-heteroarenes was developed. NH3BH3 was used as a dihydrogen surrogate, which transferred up to two equivalents of H2 per NH3BH3. Detailed spectroscopic and mechanistic studies are presented, which document the rate determination by acidic protons in the amine-borane.

Olefin-Stabilized Cobalt Nanoparticles for C=C, C=O, and C=N Hydrogenations

Sandl, Sebastian,Schwarzhuber, Felix,P?llath, Simon,Zweck, Josef,Jacobi von Wangelin, Axel

supporting information, p. 3403 - 3407 (2018/02/13)

The development of cobalt catalysts that combine easy accessibility and high selectivity constitutes a promising approach to the replacement of noble-metal catalysts in hydrogenation reactions. This report introduces a user-friendly protocol that avoids complex ligands, hazardous reductants, special reaction conditions, and the formation of highly unstable pre-catalysts. Reduction of CoBr2 with LiEt3BH in the presence of alkenes led to the formation of hydrogenation catalysts that effected clean conversions of alkenes, carbonyls, imines, and heteroarenes at mild conditions (3 mol % cat., 2–10 bar H2, 20–80 °C). Poisoning studies and nanoparticle characterization by TEM, EDX, and DLS supported the notion of a heterotopic catalysis mechanism.

Alkene Hydrogenations by Soluble Iron Nanocluster Catalysts

Gieshoff, Tim N.,Chakraborty, Uttam,Villa, Matteo,Jacobi von Wangelin, Axel

, p. 3585 - 3589 (2017/03/21)

The replacement of noble metal technologies and the realization of new reactivities with earth-abundant metals is at the heart of sustainable synthesis. Alkene hydrogenations have so far been most effectively performed by noble metal catalysts. This study reports an iron-catalyzed hydrogenation protocol for tri- and tetra-substituted alkenes of unprecedented activity and scope under mild conditions (1–4 bar H2, 20 °C). Instructive snapshots at the interface of homogeneous and heterogeneous iron catalysis were recorded by the isolation of novel Fe nanocluster architectures that act as catalyst reservoirs and soluble seeds of particle growth.

Iron-catalyzed olefin hydrogenation at 1 bar H2 with a FeCl3-LiAlH4 catalyst

Gieshoff, Tim N.,Villa, Matteo,Welther, Alice,Plois, Markus,Chakraborty, Uttam,Wolf, Robert,Jacobi Von Wangelin, Axel

, p. 1408 - 1413 (2015/03/18)

The scope and mechanism of a practical protocol for the iron-catalyzed hydrogenation of alkenes and alkynes at 1 bar H2 pressure were studied. The catalyst is formed from cheap chemicals (5 mol% FeCl3-LiAlH4, THF). A homogeneous mechanism operates at early stages of the reaction while active nanoparticles form upon ageing of the catalyst solution. This journal is

Process route upstream and downstream products

Process route

4-bromo-α-methylstyrene
6888-79-5

4-bromo-α-methylstyrene

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With [Fe3(1,1,1,3,3,3-hexamethyldisilazan-2-ide)4]Fe(η6-toluene); hydrogen; at 20 ℃; for 3h; under 1425.14 Torr; chemoselective reaction; Inert atmosphere; Glovebox;
93%
With iron(III) chloride; lithium aluminium tetrahydride; hydrogen; In tetrahydrofuran; at 18 ℃; for 20h; under 7500.75 Torr; Pressure; Inert atmosphere; Sealed tube;
92%
With 1,2-bis[(2,6-diisopropylphenyl)imino]acenaphthenecobalt(II) dibromide; hydrogen; lithium triethylborohydride; In tetrahydrofuran; at 20 ℃; for 24h; under 7500.75 Torr;
80%
4-bromo-α-methylstyrene; With lithium triethylborohydride; cobalt(II) bromide; In tetrahydrofuran; Inert atmosphere; Glovebox;
With hydrogen; In tetrahydrofuran; at 20 ℃; for 24h; under 1500.15 Torr;
20%
With ethanol; platinum; Hydrogenation;
With borane-ammonia complex; [K(thf)1.5{(2,6-diisopropylphenyl bisaryl-(imino)acenaphthene)Co(η4-1,5-cyclooctadiene)}]; hydrogen; In tetrahydrofuran; at 60 ℃; for 24h; under 7500.75 Torr; Inert atmosphere;
99 %Chromat.
Isopropylbenzene
98-82-8

Isopropylbenzene

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With aluminum oxide; bromine; for 0.0166667h; Ambient temperature;
88%
With bromine; iodine; Cooling with ice;
82%
With K10-montmorillonite clay; bromine; In tetrachloromethane; for 1.5h; Ambient temperature;
74%
With bromine; iodine; acetic acid; Irradiation;
With aluminum tri-bromide; bromine; Irradiation;
With thallium(I) nitrate; bromine; Irradiation;
With iodine; iron; at 0 ℃; Lichtausschluss; Einleiten von Brom-Dampf und Luft;
With bromine; iodine;
With bromine;
With bromine; In trifluoroacetic acid;
With bromine; In chloroform; at 0 ℃; for 2h;
110 g
With zeolite NaY; bromine; In dichloromethane; at 20 ℃; for 5h;
98 % Chromat.
With bromine;
Isopropylbenzene
98-82-8

Isopropylbenzene

1-bromo-2-isopropylbenzene
7073-94-1

1-bromo-2-isopropylbenzene

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With carbon dioxide; bromine; at 40 ℃; for 2h; under 187519 Torr; Supercritical conditions; Green chemistry;
86%
14%
With styrene-4-vinyl(N-alkylpyridinium bromide); In water; acetic acid; at 85 ℃; for 5h;
40%
10.5%
With bromine; iodine; iron; acetic acid;
With ferrocenium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate; bromine; zinc(II) oxide; In dichloromethane; at 20 ℃; for 8h;
With sulfuric acid; dihydrogen peroxide; sodium bromide; In water; at 49.84 ℃;
With sulfuric acid; dihydrogen peroxide; sodium bromide; In water; at 19.84 ℃; Further Variations:; Reagents; Temperatures; Kinetics;
With bromine; In nitromethane; at 50 ℃; for 2.5h; regioselective reaction;
With hydrogen bromide; ethylammonium nitrate; In water; at 50 ℃; for 7h; regioselective reaction; Green chemistry;
bromobenzene
108-86-1,52753-63-6

bromobenzene

isopropyl bromide
75-26-3

isopropyl bromide

1-bromo-2-isopropylbenzene
7073-94-1

1-bromo-2-isopropylbenzene

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
aluminium trichloride; at 25 ℃; for 0.75h;
95%
5%
bromobenzene
108-86-1,52753-63-6

bromobenzene

isopropyl chloride
75-29-6

isopropyl chloride

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With aluminium trichloride;
(4-bromophenyl)magnesium bromide
18620-02-5

(4-bromophenyl)magnesium bromide

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: diethyl ether / Erhitzen des nach der Hydrolyse erhaltenen Reaktionsprodukts mit Acetanhydrid
2: platinum; ethanol / Hydrogenation
With diethyl ether; ethanol; platinum;
bromobenzene
108-86-1,52753-63-6

bromobenzene

isopropyl alcohol
67-63-0,8013-70-5

isopropyl alcohol

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With boron trifluoride; anschliessendes Erwaermen mit P2O5 auf 75-85grad;
Isopropylbenzene
98-82-8

Isopropylbenzene

bromobenzene
108-86-1,52753-63-6

bromobenzene

1-bromo-2-isopropylbenzene
7073-94-1

1-bromo-2-isopropylbenzene

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With hydrogenchloride; sodium hypochlorite; sodium bromide; In water; at 19.85 ℃; for 5h; Further Variations:; Temperatures; Reagents; reagents ratio; Product distribution;
78%
7.2%
6.2%
para-bromoacetophenone
99-90-1

para-bromoacetophenone

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1.1: sodium hydride / paraffin oil; tetrahydrofuran / 20 h / 20 °C
1.2: 48 h / 20 °C
2.1: hydrogen; iron(III) chloride; lithium aluminium tetrahydride / tetrahydrofuran / 20 h / 18 °C / 7500.75 Torr / Inert atmosphere; Sealed tube
With iron(III) chloride; lithium aluminium tetrahydride; hydrogen; sodium hydride; In tetrahydrofuran; paraffin oil;
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran; paraffin oil / 20 h / 20 °C
1.2: 48 h / 20 °C
2.1: hydrogen; [Fe3(1,1,1,3,3,3-hexamethyldisilazan-2-ide)4]Fe(η6-toluene) / 3 h / 20 °C / 1425.14 Torr / Inert atmosphere; Glovebox
With [Fe3(1,1,1,3,3,3-hexamethyldisilazan-2-ide)4]Fe(η6-toluene); hydrogen; sodium hydride; In tetrahydrofuran; paraffin oil;
bromobenzene
108-86-1,52753-63-6

bromobenzene

propyl bromide
106-94-5

propyl bromide

4-iso-propylbromobenzene
586-61-8

4-iso-propylbromobenzene

Conditions
Conditions Yield
With aluminium; at 80 ℃;

Global suppliers and manufacturers

Global( 80) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Simagchem Corporation
  • Business Type:Manufacturers
  • Contact Tel:+86-592-2680277
  • Emails:sale@simagchem.com
  • Main Products:110
  • Country:China (Mainland)
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:29
  • Country:China (Mainland)
  • Shaanxi BLOOM TECH Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-29-86470566
  • Emails:sales@bloomtechz.com
  • Main Products:79
  • Country:China (Mainland)
  • Shanghai Upbio Tech Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-21-52196435
  • Emails:upbiocn@hotmail.com
  • Main Products:88
  • Country:China (Mainland)
  • Siwei Development Group Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-82881840
  • Emails:marksiwei@vip.163.com
  • Main Products:55
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 586-61-8
Post Buying Request Now
close
Remarks: The blank with*must be completed