58703-25-6

Basic information

• Product Name: 5-Methoxythiophene-2-carbonitrile
• Synonyms: 5-Methoxythiophene-2-carbonitrile
• CAS NO: 58703-25-6
• Molecular Formula: C6H5NOS
• Molecular Weight: 139.175
• Mol File: 58703-25-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Methoxythiophene-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methoxythiophene-2-carbonitrile(58703-25-6)
• EPA Substance Registry System: 5-Methoxythiophene-2-carbonitrile(58703-25-6)

Safety Data

• Hazardous Substances Data: 58703-25-6(Hazardous Substances Data)

Upstream product

• 35087-46-8 2-methoxythiophene-5-carbaldehyde 

Relevant articles and documents

PYRIMIDINE DERIVATIVE

A compound represented by the general formula (1) which has an inhibitory effect on PDE4 activity and produces little adverse side effects: wherein Ar1 represents a furyl, thienyl, triazolyl, thiazolyl, oxazolyl or benzothiazolyl group; Ar2 represents -E-AR21-G-Q (where Ar21 represents a benzene or naphthalene ring; E represents a single bond or an alkylene group; G represents a single bond, an alkylene group or an alkenylene group; and Q represents a carboxyl group, -CON(R41)(R42) or -COOR43), -E-Ar21-G2-G-Q (where E, Ar21, G and Q are as defined above; and G2 represents -O-, -S-, -SO-, -SO2- or -NRG21-) or a monocyclic aromatic heterocyclic ring other than a pyrazolyl group; R1 and R2 are the same as or different from each other and independently represent a hydrogen atom, an alkyl group which may be substituted or the like; and R3 represents a hydrogen atom or an alkyl group which may be substituted.

Elimination reactions of (Z)-thiophene- and (Z)-furan-2-carbaldehyde O- benzoyloximes. Effect of β-aryl group upon the nitrile-forming anti transition state

Elimination reactions of (Z)-thiophene- and (Z)-furan-2-carbaldehyde O- benzoyloximes 1 and 2 with DBU in MeCN have been investigated kinetically. The reactions are second order and exhibit substantial values of Hammett ρ and k(H)/k(D) values, and an E2 m