5879-91-4

Basic information

• Product Name: N-(4-methoxyphenyl)-9H-xanthene-9-carboxamide
• Synonyms: 9H-xanthene-9-carboxamide, N-(4-methoxyphenyl)-
• CAS NO: 5879-91-4
• Molecular Formula: C₂₃H₂₂O₂
• Molecular Weight: 331.3646
• Mol File: 5879-91-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 540.9°C at 760 mmHg
• Flash Point: 280.9°C
• Density: 1.275g/cm³
• Vapor Pressure: 9.12E-12mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: N-(4-methoxyphenyl)-9H-xanthene-9-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)-9H-xanthene-9-carboxamide(5879-91-4)
• EPA Substance Registry System: N-(4-methoxyphenyl)-9H-xanthene-9-carboxamide(5879-91-4)

Safety Data

• Hazardous Substances Data: 5879-91-4(Hazardous Substances Data)

Upstream product

• 71597-85-8 (p-hydroxyphenyl)boronic acid 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 1769-84-2 6-methoxy-2-phenyl-1-tetralone 
• 14088-05-2 2-Phenyl-6-methoxy-1,2,3,4-tetrahydronaphthalen-1-ol 
• 108-95-2 phenol 
• 1729-38-0 1-(p-hydroxyphenyl)-6-methoxy-2-phenyl-3,4-dihydronaphthalene 
• 108-86-1 bromobenzene 
• 6793-92-6 p-benzyloxyphenylbromide 
• 308812-06-8 4-(4-(benzyloxy)phenyl)-7-methoxy-3-phenyl-1,2-dihydronaphthalene 
• 869006-52-0 4-(4-(benzyloxy)phenyl)-3-bromo-7-methoxy-1,2-dihydronaphthalene 

Downstream Products

• 180915-78-0 lasofoxifene 
• 22845-55-2 U₂₃₄₆₉ 
• 72105-64-7 3-{(5S,6R)-5-[4-(2,3-Dihydroxy-propoxy)-phenyl]-6-phenyl-5,6,7,8-tetrahydro-naphthalen-2-yloxy}-propane-1,2-diol 
• 72105-62-5 (5S,6R)-5-(4-Hydroxy-phenyl)-6-phenyl-5,6,7,8-tetrahydro-naphthalen-2-ol 
• 72105-61-4 3-[4-((1S,2R)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-propane-1,2-diol 

Relevant articles and documents

ESTROGEN RECEPTOR TARGETING ANTAGONISTS

The present disclosure relates to compounds that act as antagonists via binding to the ER ligand binding domain non-covalently or covalently, or act as both antagonists and ER protein degraders, and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ breast cancer.

TETRAHYDRONAPHTHALENE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are tetrahydronaphthalene compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structura

Selective estrogen receptor modulators

The present invention provides, inter alia, triphenylethylene derivatives, such as, 3-{4-[6-(3-Methoxy-phenyl)-8,9-dihydro-7H-benzocyclohepten-5-yl]-phenyl}-acrylic acid, as selective estrogen receptor modulators. Also provided are methods for the treatme