5879-98-1

Basic information

• Product Name: 1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine
• Synonyms: 1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine
• CAS NO: 5879-98-1
• Molecular Weight: 427.587
• Mol File: 5879-98-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine(5879-98-1)
• EPA Substance Registry System: 1-{2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-phenoxy]-ethyl}-pyrrolidine(5879-98-1)

Safety Data

• Hazardous Substances Data: 5879-98-1(Hazardous Substances Data)

Upstream product

• 1847-63-8 1-{2-[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]ethyl}pyrrolidine hydrochloride 
• 180916-16-9 lasofoxifene 

Downstream Products

• 180916-16-9 lasofoxifene 
• 180915-78-0 (5S,6R)-6-Phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydro-naphthalen-2-ol 
• 180915-78-0 cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6,7,8-tetrahydronaphthalene2-ol 

Relevant articles and documents

Total synthesis of lasofoxifene and nafoxidine

An intramolecular reductive coupling process of diketone with low-valent titanium species to form a dihydronapthalene skeleton was an important step in the synthesis of nafoxidine (1) and lasofoxifene (2). Diketone 6 was prepared in a convenient, three-st

Method for manufacturing a low dose pharmaceutical composition having uniform drug distribution and potency

A method for manufacturing a pharmaceutical composition having uniform drug distribution and potency is described which utilizes silicon dioxide to reduce the loss of active ingredient during the manufacturing process. The method is particularly useful for the manufacture of low dosage tablet compositions.

Estrogen agonists/antagonists

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