Welcome to LookChem.com Sign In|Join Free

Cas Database

58910-37-5

58910-37-5

Identification

  • Product Name:Piperazine, 1-(2,4-dinitrophenyl)-4-methyl-

  • CAS Number: 58910-37-5

  • EINECS:

  • Molecular Weight:266.257

  • Molecular Formula: C11H14N4O4

  • HS Code:

  • Mol File:58910-37-5.mol

Synonyms:1-(2,4-dinitro-phenyl)-4-methyl-piperazine;1-(2,4-Dinitrophenyl)-4-methyl-piperazin;1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene;

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase

Relevant articles and documentsAll total 5 Articles be found

Aryl-Diadamantyl Phosphine Ligands in Palladium-Catalyzed Cross-Coupling Reactions: Synthesis, Structural Analysis, and Application

Sinai, ádám,Simkó, Dániel Cs.,Szabó, Fruzsina,Paczal, Attila,Gáti, Tamás,Bényei, Attila,Novák, Zoltán,Kotschy, András

supporting information, p. 1122 - 1128 (2020/03/03)

Synthesis, temperature-dependent NMR structure investigation and utilization of a new, stable and easily accessible aryl-diadamantylphosphine ligand family is reported. The bulky and electron-rich phosphorus center of the ligand enhances the catalytic activity of palladium in cross-coupling reactions of sterically demanding ortho-substituted aryl halides. In our study, we demonstrated the synthetic applicability of the new phosphine ligands in Buchwald-Hartwig and tosyl hydrazone coupling reactions.

Synthesis of o-Nitroarylamines via Ipso Nucleophilic Substitution of Sulfonic Acids

Manne, Srinivasa Rao,Chandra, Jyoti,Mandal, Bhubaneswar

supporting information, p. 636 - 639 (2019/01/21)

A mild, efficient, and eco-friendly method for the synthesis of o-nitroarylamine from o-nitroaryl sulfonic acid via ipso nucleophilic aryl substitution by amine is described. The products have been obtained with good yields at room temperature without the assistance of any metal, activating agent, or toxic oxidant. This method is useful for racemization-free synthesis of N-aryl amino acid esters.

DYE COMPOSITION COMPRISING A CATIONIC META-PHENYLENEDIAMINE

-

Page/Page column 34, (2014/01/18)

One subject of the invention is a meia-phenylenediamine compound having formula (I) below, the addition salts thereof with an acid and the solvates thereof: in which: ? R represents a hydrogen or halogen atom; a C1-C4 alkyl group; a carboxyl group or a (C1-C4)alkoxycarbonyl group, ? R1 represents a C1-C10(hydroxy)alkyl group, optionally interrupted with one or more non-adjacent oxygen atoms or non-adjacent NR' substituents, substituted by a cationic CAT group, ? R2 represents a hydrogen atom or a C1-C4(hydroxy)alkyl group, ? R1 and R2 may form, together with the atom that bears them, a cationic heterocycle with 5 to 8 members, ? R' represents a hydrogen atom or a C1-C4(hydroxy)alkyl group; ? An represents an anion or a mixture of anions which are organic or inorganic and cosmetically acceptable.

IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS

-

Page/Page column 113-114, (2010/04/28)

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof. The Formula (I) imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.

Structural studies of some 1-polymethyleneimino-2,4-dinitrobenzenes and related compounds; Crystal structure of 1-(cis-2′,6′-dimethylpiperidin-l′-yl)-2,4-dinitrobenzene

Mackay, Maureen F.,Gale, Douglas J.,Wilshire, John F. K.

, p. 715 - 722 (2007/10/03)

The ultraviolet and 1H n.m.r. spectra of some 1-polymethyleneimino-2,4-dinitrobenzenes and related compounds are discussed. The effect of trifluoroacetic acid on these spectra was also investigated; with 1-azetidiny 1-2,4-dinitrobenzene, acid-c

Process route upstream and downstream products

Process route

1-methyl-piperazine
109-01-3

1-methyl-piperazine

2,4-Dinitrofluorobenzene
70-34-8,65727-75-5

2,4-Dinitrofluorobenzene

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene
58910-37-5

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene

Conditions
Conditions Yield
98%
With potassium carbonate; In acetonitrile; at 120 ℃; for 0.5h; Microwave irradiation;
89.5%
With triethylamine; In dimethyl sulfoxide; Heating;
84%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

2,4-dinitrobenzenesulfonic acid
89-02-1

2,4-dinitrobenzenesulfonic acid

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene
58910-37-5

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene

Conditions
Conditions Yield
In tetrahydrofuran; at 20 ℃; for 0.5h; Green chemistry;
88%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

1-chloro-2,4-dinitro-benzene
97-00-7

1-chloro-2,4-dinitro-benzene

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene
58910-37-5

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene

Conditions
Conditions Yield
With tris-(dibenzylideneacetone)dipalladium(0); di(1-adamantyl)-4-(N,N-dimethyl)amino-phenyl-phosphane trifluoroacetic acid; sodium t-butanolate; In toluene; at 80 ℃; Sealed tube; Inert atmosphere;
71%
With ethanol;
1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene
58910-37-5

1-(4'-methylpiperazin-1'-yl)-2,4-dinitrobenzene

dimethyl sulfate
77-78-1

dimethyl sulfate

4-(2,4-dinitrophenyl)-1,1-dimethylpiperazin-1-ium methyl sulfate

4-(2,4-dinitrophenyl)-1,1-dimethylpiperazin-1-ium methyl sulfate

Conditions
Conditions Yield
In tetrahydrofuran; at 20 ℃; for 3h;
100%

Global suppliers and manufacturers

Global( 0) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 58910-37-5
Post Buying Request Now
close
Remarks: The blank with*must be completed