590-14-7 Usage
Chemical Properties
CLEAR COLOURLESS TO LIGHT YELLOW LIQUID
Uses
Different sources of media describe the Uses of 590-14-7 differently. You can refer to the following data:
1. 1-Propenyl bromide is a useful building block, especially when a 3 carbon addition is required, such as its use in the synthesis of the pharmaceutical spilanthol.
2. 1-Bromo-1-propene upon n-BuLi treatment generates the propynyllithium anion, in situ, which later undergoes nucleophilic addition reactions. Some of its other applications are:Synthesis of organic reagents such as methyl but-2-ynoate and 1-iodopropyne.Preparation o f intermediates in the total synthesis of (+)-aphanamol I and skyllamycins A-C.Synthesis of allylated pyrazoles, aryl alkynyl sulfides and allenamides.
Synthesis Reference(s)
The Journal of Organic Chemistry, 56, p. 4066, 1991 DOI: 10.1021/jo00012a053
Check Digit Verification of cas no
The CAS Registry Mumber 590-14-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 0 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 590-14:
(5*5)+(4*9)+(3*0)+(2*1)+(1*4)=67
67 % 10 = 7
So 590-14-7 is a valid CAS Registry Number.
InChI:InChI=1/C3H5Br/c1-2-3-4/h2-3H,1H3
590-14-7Relevant articles and documents
Ultrasonically Assisted Decarboxylative Bromination of α,β-Unsaturated Carboxylic Acids under Vilsmeier-Haack Conditions
Kumar, M. Satish,Rajanna,Venkanna,Venkateswarlu,Sudhakar Chary
, p. 642 - 646 (2015/12/26)
An efficient method for decarboxylative bromination of cinnamic acids (α,β-unsaturated carboxylic acids or 3-arylpropenoic acids) was achieved under relatively mild conditions using Vilsmeier-Haack reagent and KBr in acetonitrile media. Vilsmeier-Haack reagent is prepared by using 1:1 ratio of oxychloride (SOCl2 or POCl3) and DMF under chilled condition. Ultrasonically assisted reactions underwent smoothly with highly significant rate enhancements and afforded bromostyrenes as products in very good yields even though the reactions were too sluggish.
Synthesis of hydroxylated hydrocarbons
-
Page/Page column 5, (2008/06/13)
Ethylene glycol, other diols, triols, and polyols are made in an efficient manner by reacting dibromides with water in the presence of a metal oxide. An integrated process of dibromide formation, alcohol synthesis, metal oxide regeneration, and bromine recycling is also provided.
