59142-57-3

Basic information

• Product Name: (2-bromo-4-methoxyphenyl)phenylmethanone
• Synonyms: (2-bromo-4-methoxyphenyl)phenylmethanone
• CAS NO: 59142-57-3
• Molecular Weight: 291.144
• Mol File: 59142-57-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2-bromo-4-methoxyphenyl)phenylmethanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-bromo-4-methoxyphenyl)phenylmethanone(59142-57-3)
• EPA Substance Registry System: (2-bromo-4-methoxyphenyl)phenylmethanone(59142-57-3)

Safety Data

• Hazardous Substances Data: 59142-57-3(Hazardous Substances Data)

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 43192-31-0 2-bromo-4-methoxybenzaldehyde 
• 74317-85-4 2-bromo-4-methoxybenzoic acid 
• 59142-59-5 (2-Bromo-4-methoxy-phenyl)-phenyl-methanol 
• 2398-37-0 3-methoxyphenyl bromide 
• 98-88-4 benzoyl chloride 

Downstream Products

• 74317-85-4 2-bromo-4-methoxybenzoic acid 
• 611-94-9 4-Methoxybenzophenone 
• 15144-82-8 3-methoxy-fluoren-9-one 

Relevant articles and documents

Palladium(II)-catalyzed Intermolecular Cascade Cyclization of Methylenecyclopropanes with Aromatic Alkynes: Construction of Spirocyclic Compounds Containing Indene and 1,2-Dihydronaphthalene Moieties

A palladium(II)-catalyzed intermolecular cascade cyclization of methylenecyclopropanes with aromatic alkynes is reported in this paper. The reaction involves a migratory insertion of alkyne, an intramolecular Heck-type reaction, and β-H elimination, providing a series of spirocyclic compounds containing indene and 1,2-dihydronaphthalene moieties in moderate to excellent yields upon heating.

Enantioselective N-Heterocyclic Carbene Catalyzed Synthesis of Functionalized Indenes

An enantioselective NHC (N-heterocyclic carbene) catalyzed synthesis of indenes from bifunctional α,β-unsaturated acyl fluorides and TMS enol ethers has been discovered. The reaction has broad generality (31 examples) and proceeds with high levels of enantioselectivity (most >92:8 er). Mechanistically the reaction likely occurs via a Michael/β-lactonization/decarboxylation sequence. Derivatization studies and limitations are discussed.

Catalytic Friedel-Crafts acylation: Magnetic nanopowder CuFe 2O4 as an efficient and magnetically separable catalyst

Catalytic regioselective Friedel-Crafts acylation of an array of anisoles/arenes with various acid chlorides using 5-20 mol % of magnetic nanopowder CuFe2O4 is reported. Unlike the conventional Friedel-Crafts reactions, which are catalyzed by moisture sensitive homogeneous catalysts/promoters, the nanopowder CuFe2O4 catalyst is moisture insensitive and the product/ketone-catalyst isolation is easily achieved using the magnetic properties of CuFe2O4.