59204-74-9

Basic information

• Product Name: EGOMAKETONE
• Synonyms: EGOMAKETONE;1-(3-Furyl)-4-methyl-3-penten-1-one
• CAS NO: 59204-74-9
• Molecular Formula: C10H12O2
• Molecular Weight: 164.2
• Mol File: 59204-74-9.mol

Chemical Properties

• Boiling Point: 244.6°C at 760 mmHg
• Flash Point: 106.5°C
• Appearance: /
• Density: 1.006g/cm³
• Vapor Pressure: 0.03mmHg at 25°C
• Refractive Index: 1.487
• CAS DataBase Reference: EGOMAKETONE(CAS DataBase Reference)
• NIST Chemistry Reference: EGOMAKETONE(59204-74-9)
• EPA Substance Registry System: EGOMAKETONE(59204-74-9)

Safety Data

• Hazardous Substances Data: 59204-74-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12O2/c1-8(2)3-4-10(11)9-5-6-12-7-9/h3,5-7H,4H2,1-2H3

Upstream product

• 201230-82-2 carbon monoxide 
• 87453-06-3 tributyl(furan-3-yl)stannane 
• 870-63-3 prenyl bromide 
• 123030-45-5 1-furan-3-yl-4-methyl-pent-3-en-1-ol 
• 82187-40-4 1-Furan-3-yl-4-methyl-2-(2-methylamino-benzenesulfonyl)-pent-3-en-1-one 
• 78952-50-8 3-(Trimethylstannyl)furan 
• 503-60-6 3,3-dimethyl-allyl chloride 
• 82187-36-8 Furan-3-carboxylic acid methyl-[2-(3-methyl-but-2-enylsulfanyl)-phenyl]-amide 
• 82187-38-0 Furan-3-carboxylic acid methyl-[2-(3-methyl-but-2-ene-1-sulfonyl)-phenyl]-amide 

Relevant articles and documents

Regiospecific synthesis of 3,4-disubstituted furans and 3-substituted furans using 3,4-bis(tri-n-butylstannyl)furan and 3-(tri-n-butylstannyl)furan as building blocks

3,4-Bis(tri-n-butylstannyl)furan and 3-(tri-n-butylstannyl)furan have been prepared and used successfully as building blocks to lead to various 3,4-disubstituted furans and 3-substituted furans, respectively.

PALLADIUM-CATALYZED CROSS COUPLING OF ALLYL HALIDES WITH ORGANOTIN REAGENTS: A METHOD OF JOINING HIGHLY FUNCTIONALIZED PARTNERS REGIOSELECTIVELY AND STEREOSPECIFICALLY.

The palladium-catalyzed reaction of allyl halides with aryl- and vinyltin reagents gives high yields of cross-coupled products. In the presence of 1-3 atm of carbon monoxide, ketones are obtained, resulting from cross coupling accompanied by carbon monoxide insertion. The reaction is mild and tolerant of a wide variety of functionalities (OH, OR, CN, CO//2R, CHO) on either the allyl chloride or the tin reagent. Coupling at the allyl halide partner proceeds with inversion of configuration at the carbon bearing the halide, with retention of geometry at the allylic double bond, and with a regioselectivity for the least-substituted carbon in the allylic framework. Retention of double-bond geometry is observed in the vinyltin partner.