5957-75-5

Basic information

• Product Name: DELTA-8-THC
• Synonyms: (-)-delta(sup6)-3,4-trans-tetrahydrocannabinol;(-)-delta(sup8)-trans-tetrahydrocannabinol;(-)-trans-delta(sup8)-tetrahydrocannabinol;1-trans-delta(sup8)-tetrahydro-cannabino;1-trans-delta(sup8)-tetrahydrocannabinol;d)pyran-1-ol,6a,7,10,10a-tetrahydro-3-pentyl-6,6,9-trimethyl-6h-dibenzo(tr;d)pyran-1-ol,6a,7,10,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6h-dibenzo(;delta(sup6)-thc
• CAS NO: 5957-75-5
• Molecular Formula: C₂₁H₃₀O₂
• Molecular Weight: 314.46
• EINECS: 200-659-6
• Product Categories: Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 5957-75-5.mol
• Article Data: 18

Chemical Properties

• Boiling Point: bp0.001 200°
• Flash Point: 11 °C
• Appearance: /ethanol solution
• Density: 1.0536 (rough estimate)
• Vapor Pressure: 1.98E-06mmHg at 25°C
• Refractive Index: 1.5404 (estimate)
• Storage Temp.: −20°C
• PKA: 9.83±0.60(Predicted)
• CAS DataBase Reference: DELTA-8-THC(CAS DataBase Reference)
• NIST Chemistry Reference: DELTA-8-THC(5957-75-5)
• EPA Substance Registry System: DELTA-8-THC(5957-75-5)

Safety Data

• Hazard Codes: F,T
• Statements: 11-39/23/24/25-23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN 1170 3/PG 2
• WGK Germany: 1
• Hazardous Substances Data: 5957-75-5(Hazardous Substances Data)

Usage

Uses

It is one of the active constituent of cannabis. Agonist at CB1 and CB2 cannabinoid receptors. Antiemetic; appetite stimulant. Controlled substance (hallucinogen).

InChI:InChI=1/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h9,12-13,16-17,22H,5-8,10-11H2,1-4H3/t16-,17-/m1/s1

Upstream product

• 20053-58-1 (1S,2S,3R,6R)-(+)-trans-car-2-ene epoxide 
• 500-66-3 Olivetol 
• 13956-29-1 CBD 
• 13956-30-4 (-)-5'-methyl-4-pentyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro-[1,1'-biphenyl]-2,6-diol 
• 23978-85-0 tetrahydrocannabinolic acid 
• 119678-39-6 (3S,4R)-1-p-menthene-3,8-diyl carbonate 
• 781642-49-7 5-pentyl-1,3-benzenediol/β-cyclodextrin complex 
• 936-91-4 3-carene epoxide 
• 1686-20-0 p‐mentha‐1,5‐dien‐8‐ol 
• 88510-95-6 (6aR,9S,10aR)-9α-bromo-6a,10a-trans-hexahydrocannabinol 

Downstream Products

• 132213-93-5 (-)-1-O-(biphenylylmethyl)-Δ^9,11-tetrahydrocannabinol 
• 132213-87-7 (-)-1-O-(4-aminobutyl)-Δ⁸-tetrahydrocannabinol 
• 27179-29-9 (-)-1-O-methyl-Δ^9,11-tetrahydrocannabinol 
• 1972-08-3 dronabinol 
• 27179-28-8 (+/-)-delta7-Tetrahydrocannabinol 
• 876625-59-1 3'-hydroxy-Δ8-tetrahydrocannabinol 
• 28646-40-4 11-hydroxy-Δ8-tetrahydrocannabinol 
• 33886-04-3 1'-hydroxy-Δ8-tetrahydrocannabinol 
• 37936-81-5 7beta-Hydroxy-D₈-tetrahydrocannabinol 
• 1451-20-3 (-)-O-methyl-Δ⁸-tetrahydrocannabinol 
• 132213-91-3 (-)-1-O-(biphenylylmethyl)-Δ⁸-tetrahydrocannabinol 

Relevant articles and documents

MASS PRODUCTION AND APPLICATION OF DELTA 8 THC

A process of converting cannabidiol (CBD) to Δ8-tetrahydrocannabinol (Δ8-THC) or Δ9-tetrahydrocannabinol (Δ9-THC) can enable mass production of Δ8-THC and/or Δ9-THC, achieve greater yields and higher purity in comparison to previously reported processes while eliminating the use of organic solvent. The resultant hemp-derived Δ8-THC can be mixed with and absorbed by natural extracts, including tea extract, starch, sugar, lecithin, and other emulsifiers. Δ8-THC used in edible, topical and vaping products such as powdered Δ8-THC food ingredients, tablets or pills, suppositories, and vape formulations are disclosed. Further described are beverages and baked goods utilizing or incorporating the tablets or powdered Δ8-THC to create edible products containing an emulsified, tasteless, and odorless dose of Δ8-THC. The disclosure also describes a rectal suppository designed to provide improved comfort of use. A Δ8-THC liquid composition can be use in an electronic cigarette smoking device for pulmonary administration of Δ8-THC, which results in more effective absorption.

METHODS FOR PREPARING CANNABINOIDS AND RELATED INSTRUMENTS

Methods and instrumentation for converting cannabidiol (CBD) and CBD-like compounds to other naturally-occurring or synthetic cannabinoids, such as THC, CBN and/or CBC, which processes may be solvent-free, Generally, the conversion of CBD is carried out in the presence of a Lewis acid, an oxidant or both, which may be present in catalytic amounts. A reaction may be a two-phase reaction with the Lewis acid present on a support material in a column or similar chamber through which CBD passes and is converted to the cannabinoids. The reactions allow direction of relative yields of certain cannabinoid products by altering the identity of the acid reagent.

NOVEL METHODS AND RELATED TOOLS FOR CBD CONVERSION TO THC

The present invention is directed to methods of producing THC from CBD utilizing non-harsh methodology and resulting in substantially increased yields, as well as devices built upon these novel methods. The methods and devices are material efficient, and in certain embodiments, solvent-free. In particular, in certain embodiments, these methods and related devices are suitable for commercial production of THC from CBD. Furthermore, in certain embodiments, the present invention provides methods of producing THC from CBD in manner that affords tunability to select the ratio of THC -8 to THC-9.