59608-97-8

Basic information

• Product Name: 2-Amino-4-chloromethythiazole hydrochloride
• Synonyms: 2-AMINO-4-(CHLOROMETHYL)THIAZOLE HCI;2-thiazolamine, 4-(chloromethyl)-;4-(chloromethyl)-1,3-thiazol-2-amine hydrochloride;4-(Chloromethyl)-1,3-thiazol-2-ylamine hydrochloride;2-AMino-4-chloroMethythiazole, HCl;2-ThiazolaMine,4-(chloroMethyl)-, hydrochloride;2-AMINO-4-(CHLOROMETHYL)THIAZOLE HCL;2-AMINO-4-(CHLOROMETHYL)THIAZOLE HYDROCHLORIDE
• CAS NO: 59608-97-8
• Molecular Formula: C₄H₅ClN₂S*ClH
• Molecular Weight: 185.07
• EINECS: 1592732-453-0
• Product Categories: Thiazole
• Mol File: 59608-97-8.mol
• Article Data: 11

Chemical Properties

• Melting Point: 141-143 °C(Solv: ethanol (64-17-5))
• Boiling Point: 299.7 °C at 760 mmHg
• Flash Point: 135 °C
• Appearance: /
• Density: 1.455g/cm³
• Vapor Pressure: 0.00118mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Amino-4-chloromethythiazole hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-4-chloromethythiazole hydrochloride(59608-97-8)
• EPA Substance Registry System: 2-Amino-4-chloromethythiazole hydrochloride(59608-97-8)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37
• HazardClass: IRRITANT
• Hazardous Substances Data: 59608-97-8(Hazardous Substances Data)

Usage

General Description

2-Amino-4-chloromethythiazole hydrochloride is a chemical compound that belongs to the thiazole class of molecules. It is a synthetic organic compound with the molecular formula C4H6ClN3S·HCl. 2-Amino-4-chloromethythiazole hydrochloride is used in the pharmaceutical industry as a raw material for the synthesis of various drugs and has potential biological activities. It is a white to off-white crystalline powder that is soluble in water and moderately soluble in methanol. 2-Amino-4-chloromethythiazole hydrochloride is used as a key intermediate in the production of medicines and is a valuable compound in the field of medicinal chemistry.

InChI:InChI=1/C4H5ClN2S/c5-1-3-2-8-4(6)7-3/h2H,1H2,(H2,6,7)

Upstream product

• 17356-08-0 thiourea 
• 534-07-6 1,3-Dichloroacetone 

Downstream Products

• 1603-91-4 4-methylthiazol-2-ylamine 
• 51307-43-8 2-amino-4-hydroxymethylthiazole 
• 116252-53-0 4-((dimethylamino)methyl)thiazole-2-amine 
• 17386-09-3 4-pyrrolidin-1-ylmethyl-thiazol-2-ylamine 
• 17386-10-6 4-piperidin-1-ylmethyl-thiazol-2-ylamine 
• 3008-61-5 4-(morpholinomethyl)thiazol-2-amine 
• 17386-11-7 4-azepan-1-ylmethyl-thiazol-2-ylamine 
• 7460-59-5 N-(4-(chloromethyl)thiazol-2-yl)acetamide 
• 372509-58-5 (2-amino-thiazol-4-yl)-methanol; hydrochloride 
• 133691-45-9 4-[(4-nitro-phenylsulfanyl)-methyl]-thiazol-2-ylamine 
• 1003584-27-7 1-(3-fluorobenzyl)-3-(4-(chloromethyl)thiazol-2-yl)urea 
• 1108653-16-2 1-(3,5-difluorobenzyl)-3-(4-chloromethylthiazol-2-yl) urea 
• 1446194-09-7 (2Z)-{[(2-amino-1,3-thiazol-4-yl)methoxy]imino}(3-methoxyphenyl)acetonitrile 
• 21679-21-0 thiosulfuric acid S-(2-amino-thiazol-4-ylmethyl) ester 

Relevant articles and documents

Structure-activity relationship studies of antiplasmodial aminomethylthiazoles

Structure-activity relationship (SAR) studies around a previously reported antimalarial aminomethylthiazole pyrazole carboxamide 1 are reported. Several analogues were synthesised and profiled for in vitro antiplasmodial activity against the drug-sensitiv

N -substituted -2 - amino -4 - saccharin-substituted methylthiazole compound with bactericidal activity Preparation method and application

N -substituted -2 - amino -4 - saccharin-substituted methylthiazole compounds with bactericidal activity, a preparation method and an application thereof relate to the technical field of organic synthesis and agricultural chemicals. Experiments prove that

NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR

[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)