597-32-0Relevant articles and documents
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Hurd,Abernethy
, p. 976 (1941)
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Reactions of 2-substituted epichlorohydrins
Tanyeli,Demir,Akhmedov,Ozgul,Kandemir
, p. 2967 - 2980 (2007/10/03)
2-Substituted epichlorohydrins have been synthesized by starting with 1,2-dichloro acetone and various alkyl and aryl halides via dichlorohydrins followed by cyclization. The reactive 2-substituted epichlorohydrins were subjected to nucleophilic attacking of azide and cyanide ions to afford corresponding β-azido alcohols and α,β-unsaturated nitriles.
Synthesis and pharmacological study of aryloxypropanolamines substituted on carbon 2
Galons,Combet Farnoux,Miocque,et al.
, p. 23 - 27 (2007/10/02)
In a series of aryloxypropanolamines, substitution on carbon 2 by alkyl, aryl or aralkyl groups lowers the β-blocking activity. This effect increases with the size of the substituent.
