5977-99-1

Basic information

• Product Name: 2-anilinoethanethiol
• Synonyms: 2-anilinoethanethiol
• CAS NO: 5977-99-1
• Molecular Formula: C₈H₁₁NS
• Molecular Weight: 153.2446
• Mol File: 5977-99-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 281.3 °C at 760 mmHg
• Flash Point: 123.9 °C
• Appearance: /
• Density: 1.098 g/cm³
• Vapor Pressure: 0.00359mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 2-anilinoethanethiol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-anilinoethanethiol(5977-99-1)
• EPA Substance Registry System: 2-anilinoethanethiol(5977-99-1)

Safety Data

• Hazardous Substances Data: 5977-99-1(Hazardous Substances Data)

Usage

General Description

2-Anilinoethanethiol is a chemical compound with the molecular formula C8H11NS. It is a yellowish to brownish liquid with a pungent odor and is used primarily as an intermediate in the production of dyes, pharmaceuticals, and organic chemicals. It is also used as a corrosion inhibitor and as a stabilizer for polymers. Additionally, it has been studied for its potential role in electrochemical and biological applications. The compound is known for its strong nucleophilic properties and can undergo various reactions to form a wide range of derivatives. However, it is important to handle and store 2-anilinoethanethiol with caution, as it is considered harmful if ingested, inhaled, or absorbed through the skin, and exposure can cause irritation and potential allergic reactions.

InChI:InChI=1/C8H11NS/c10-7-6-9-8-4-2-1-3-5-8/h1-5,9-10H,6-7H2

Upstream product

• 62-53-3 aniline 
• 60-24-2 2-hydroxyethanethiol 
• 122-98-5 2-Anilinoethanol 
• 5628-96-6 ethyl 2-mercaptoethyl carbonate 
• 1005-66-9 N-(β-bromoethyl)aniline hydrobromide 
• 16181-67-2 S-(2-anilino-ethyl)-isothiourea; dihydrobromide 
• 420-12-2 thirane 

Downstream Products

• 35225-28-6 N-(2-Mercaptoethylthioethyl)anilin 
• 107273-39-2 N,N-dimethyl-4-(3-phenyl-thiazolidin-2-yl)-aniline 
• 103856-28-6 2,2-dimethyl-3-phenyl-thiazolidine 
• 94299-25-9 4,5-diphenyl-3,4-dihydro-2H-[1,4]thiazine 
• 57107-21-8 N-[2-(2,4,6-trinitro-phenylsulfanyl)-ethyl]-aniline 
• 91426-52-7 5-methyl-4-phenyl-3,4-dihydro-2H-[1,4]thiazine 
• 92288-23-8 4-phenyl-5,6-dihydro-4H-[1,4]thiazine-3-carboxylic acid 
• 62941-08-6 5,7-dinitro-4-phenyl-3,4-dihydro-2H-benzo[1,4]thiazine 
• 21089-36-1 3-phenylthiazolidin-2-one 
• 1437-99-6 3-phenyl-1,3-thiazolidine-2-thione 
• 80887-92-9 1-(β-phenylaminoethylthio)-2,6-dinitrobenzene 
• 95166-14-6 4,5,6-triphenyl-3,4-dihydro-2H-[1,4]thiazine 
• 92251-08-6 3-methyl-4-phenyl-5,6-dihydro-4H-[1,4]thiazine-2-carboxylic acid ethyl ester 
• 92247-05-7 4-phenyl-3,4,5,6,7,8-hexahydro-2H-benzo[1,4]thiazine 

Relevant articles and documents

Oligomerisation reactions of beta substituted thiols in water

Beta substituted thiols and various derivatives containing the HX-C-C-SH motif oligomerise in water, preferably in the presence of a carbonate salt. The reaction yields oligomers consisting of one thiol end group, a thiaethylene backbone and an additional terminal group corresponding to the starting material used. Mechanistic studies, as well as the scope of substrates and products of these new promising condensation processes, are presented. In addition, strong nucleophiles were also reacted with mercaptoethanol under simple reaction conditions, leading to the selective formation of more complex molecules.

Syntheses de β-sultames (thiazetidines-1,2 dioxyde-1,1)

β-sultams (1,2-thiazetidine-1,1-dioxides) are easily prepared by 1-halogensulphonyl-2-aminoalkane cyclisation. Two processes based upon this principle have permitted the preparation of many variously N and C-substituted β-sultams. 1) In the first method 1-chlorosulphonyl-2-aminoalkane hydrochlorides, prepared from taurines or β-aminothiols, cyclised in the presence of base. 2) The second process involves the spontaneous cyclisation of 1-fluorosulphonyl-2-aminoalkanes prepared Michael addition of primary amines to 1-fluorosulphonylethene.