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59834-06-9

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59834-06-9 Usage

General Description

2-(1,2,3-THIADIAZOL-4-YL)BENZENOL, also known as 4-(1,2,3-thiadiazol-4-yl)phenol, is a chemical compound with the molecular formula C7H5N3OS. It is a heterocyclic aromatic compound with a thiadiazole ring and a phenol group. This chemical is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its unique structure and properties. It may also have potential applications in materials science and organic chemistry. Its precise uses and properties in various applications are still being explored, and further research is ongoing to fully understand its potential uses and effects.

Check Digit Verification of cas no

The CAS Registry Mumber 59834-06-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,8,3 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 59834-06:
(7*5)+(6*9)+(5*8)+(4*3)+(3*4)+(2*0)+(1*6)=159
159 % 10 = 9
So 59834-06-9 is a valid CAS Registry Number.

59834-06-9Relevant articles and documents

Diiiodine/Potassium Persulfate Mediated Synthesis of 1,2,3-Thiadiazoles from N -Tosylhydrazones and a Thiocyanate Salt as a Sulfur Source under Transition-Metal-Free Conditions

Lu, Yuhan,Sun, Yadong,Abdukader, Ablimit,Liu, Chenjiang

supporting information, p. 1044 - 1048 (2021/05/05)

A highly efficient method for the synthesis of 1,2,3-thiadiazoles has been developed by utilizing readily available tosylhydrazones and ammonium thiocyanate with ecofriendly EtOH as the solvent at room temperature. The reaction shows a wide scope of subst

I2/CuCl2-promoted one-pot three-component synthesis of aliphatic or aromatic substituted 1,2,3-thiadiazoles

Wang, Can,Geng, Xiao,Zhao, Peng,Zhou, You,Wu, Yan-Dong,Cui, Yan-Fang,Wu, An-Xin

supporting information, p. 8134 - 8137 (2019/07/15)

An efficient I2/CuCl2-promoted one-pot three-component strategy for the construction of 1,2,3-thiadiazoles from aliphatic- or aromatic-substituted methyl ketones, p-toluenesulfonyl hydrazide, and potassium thiocyanate has been develo

The synthesis and biological evaluation of para-substituted phenolic N-alkyl carbamates as endocannabinoid hydrolyzing enzyme inhibitors

Minkkilae, Anna,Myllymaeki, Mikko J.,Saario, Susanna M.,Castillo-Melendez, Joel A.,Koskinen, Ari M.P.,Fowler, Christopher J.,Leppaenen, Jukka,Nevalainen, Tapio

experimental part, p. 2994 - 3008 (2009/10/10)

A series of para-substituted phenolic N-alkyl carbamates were evaluated for their FAAH and MGL inhibitory activities. The compounds were generally selective for FAAH, with IC50 values in the nM range, whereas inhibition of MGL required concentrations three orders of magnitude higher. The most potent compounds, dodecylcarbamic acid 4-(4,5-dihydrothiazol-2-yl)phenyl (12) and 4-(1,2,3-thiadiazol-4-yl)phenyl (26) esters, inhibited FAAH and MGL with IC50 values at the low-nanomolar (IC50s; 0.0063 and 0.012 μM) and the low-micromolar ranges (IC50s; 2.1 and 1.0 μM), respectively. Compound 26 also inhibited both FAAH-dependent AEA uptake and AEA hydrolysis (IC50; 0.082 μM) by intact RBL2H3 cells, and could also reduce 2-AG hydrolysis by these cells at concentrations ≥0.030 μM.

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