599-64-4

Basic information

• Product Name: p-Cumylphenol
• Synonyms: Phenol, p-(a,a-dimethylbenzyl)- (6CI,7CI,8CI);2-(4-Hydroxyphenyl)-2-phenylpropane;2-Phenyl-2-(4-hydroxyphenyl)propane;4-(1-Methyl-1-phenylethyl)phenol;4-(Dimethylphenylmethyl)phenol;4-(a,a-Dimethylbenzyl)phenol;4-Cumylphenol;4-Hydroxydiphenyldimethylmethane;NSC 6237;p-(a,a-Dimethylbenzyl)phenol;p-(a-Cumyl)phenol;p-Cumylphenol
• CAS NO: 599-64-4
• Molecular Formula: C₁₅H₁₆O
• Molecular Weight: 212.29
• EINECS: 209-968-0
• Mol File: 599-64-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 72-75℃
• Boiling Point: 338.5 °C at 760 mmHg
• Flash Point: 160.5 °C
• Appearance: cream solid
• Density: 1.055 g/cm³
• Vapor Pressure: 0.000207mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: p-Cumylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: p-Cumylphenol(599-64-4)
• EPA Substance Registry System: p-Cumylphenol(599-64-4)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S26:; S37/39:
• Hazardous Substances Data: 599-64-4(Hazardous Substances Data)

Usage

General Description

p-Cumylphenol, also known as 4-Isopropylphenol, is a chemical compound that belongs to the group of phenols. It is a white solid with a faint odor and is soluble in organic solvents such as ethanol and ether. p-Cumylphenol is commonly used as an intermediate in the production of antioxidants, stabilizers, and UV absorbers in the plastic and rubber industries. It is also employed as an intermediate in the production of pharmaceuticals, disinfectants, and fragrances. Additionally, p-Cumylphenol is known to have antimicrobial properties and is used in various personal care and cosmetic products. However, prolonged or repeated exposure to p-Cumylphenol may cause skin or eye irritation, and it should be handled with proper safety measures.

InChI:InChI=1/C15H16O/c1-12(11-13-5-3-2-4-6-13)14-7-9-15(16)10-8-14/h2-10,12,16H,11H2,1H3

Upstream product

• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 108-95-2 phenol 
• 7446-70-0 aluminium trichloride 
• 98-82-8 Isopropylbenzene 
• 10035-10-6 hydrogen bromide 
• 52820-06-1 toluene-2,4-di(carbamic acid (4-cumylphenyl) ester) 
• 98-83-9 isopropenylbenzene 
• 103-73-1 Phenetole 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 934-53-2 cumenyl chloride 
• 80-05-7 BPA 
• 80-15-9 Cumene hydroperoxide 
• 20056-52-4 tri-4-(2-phenylisopropyl)phenyl phosphate 
• 1940-95-0 1-ethoxy-4-(2-phenylpropan-2-yl)benzene 

Downstream Products

• 56949-68-9 1-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-propan-2-ol 
• 59426-97-0 Butane-2-sulfonic acid 4-(1-methyl-1-phenyl-ethyl)-phenyl ester 
• 56949-59-8 cumylphenyl monoethylene glycol ether 
• 85976-28-9 4,4,4-Trichloro-3-hydroxy-butyric acid 4-(1-methyl-1-phenyl-ethyl)-phenyl ester 
• 83482-57-9 4-[4-(1-methyl-1-phenylethyl)phenoxy]-1,2-dicyanobenzene 
• 71728-47-7 6-Diazo-5-oxo-5,6-dihydro-naphthalene-1-sulfonic acid 4-(1-methyl-1-phenyl-ethyl)-phenyl ester 
• 33524-49-1 bis(p-cumyl-phenyl)carbonate 
• 83505-35-5 2,6-Bis(2-hydroxy-5-cumylbenzyl)-4-cumylphenol 
• 165684-94-6 3-(4-cumylphenoxy)phthalonitrile 
• 4030-49-3 4-Methoxy-1-(4-α-cumyl-phenoxy)-benzol 
• 3983-66-2 4-Phenoxy-1-(4-α-cumyl-phenoxy)-benzol 
• 2316-17-8 2-Phenyl-2-<4-carbamoylmethoxy-phenyl>-propan 
• 72633-30-8 2-hydroxy-5-(2-phenyl-2-propyl)-benzaldehyde 
• 75551-85-8 2-Aminomethyl-4-(1-methyl-1-phenyl-ethyl)-phenol; hydrochloride 

Relevant articles and documents

MULTISTEP PROCESS FOR THE PREPARATION OF HEXAMETHYLENE DIISOCYANATE, PENTAMETHYLENE DIISOCYANATE OR TOLUENE DIISOCYANATE

The present invention relates to a multistep process for the preparation of organic diisocyanates by converting the corresponding diamine precursors, urea and hydroxy compounds into monomeric diurethanes, converting these diurethanes into diurethanes of high boiling hydroxy compounds, and finally cleavage of the latter diurethanes to form the diisocyanates and recover the high boiling hydroxy compounds.

METHOD FOR MANUFACTURING α-METHYLSTYRENATED PHENOL

According to an embodiment of the present invention, the present invention provides a method for manufacturing α-methyl styrenated phenol, which comprises the following steps: (a) making phenol react with α-methyl styrene (AMS) under the presence of a first acidic catalyst to obtain a first product; and (b) additionally making 1-5 equivalents of α-methyl styrene for 1 equivalent of phenol react with the first product under the presence of a second acidic catalyst to obtain a second product. The manufactured α-methyl styrenated phenol does not generate environmental damage and is economical.(a) Making phenol react with α-methyl styrene (AMS) under the presence of a first acidic catalyst(AA) Obtaining 30-50 wt% of TMPI, 1-10 wt% DMP, 5-20 wt% of cumyl phenol, 1-10 wt% of AMS trimer, and the remaining phenol(b) Additionally making the α-methyl styrene react with a first product under the presence of a second acidic catalyst(BB) Obtaining 5-50 wt% of TMPI + DMP, 2-20 wt% of cumyl phenol, 1-10 wt% of dicumene, 20-60 wt% of dicumyl phenol, and 0.1-5 wt% of AMS trimerCOPYRIGHT KIPO 2017

Calcium-catalyzed hydroarylation of alkenes at room temperature

Calcium-catalyst gaining ground: A variety of electron-poor electron-rich and trisubstituted styrene derivatives were reacted to give the desired diarylalkanes within less than an hour at room temperature in the presence of 2.5 mol % of Ca(NTf2)2/Bu4NPF6 (see scheme). Additionally the highly reactive calcium catalyst was successfully applied for the hydroarylation of dienes and even trisubstituted olefins.