59920-85-3

Basic information

• Product Name: 2-AMINO-5-(METHYLTHIO)BENZOTRIFLUORIDE
• Synonyms: 4-METHYLTHIO-2-TRIFLUOROMETHYL-ANILINE;2-AMINO-5-(METHYLTHIO)BENZOTRIFLUORIDE;2-Amino-5-(methylthio)benzotrifluoride97%;4-(Methylsulfanyl)-2-(trifluoroMethyl)aniline
• CAS NO: 59920-85-3
• Molecular Formula: C₈H₈F₃NS
• Molecular Weight: 207.22
• Mol File: 59920-85-3.mol

Chemical Properties

• Boiling Point: 264.8 °C at 760 mmHg
• Flash Point: 113.9 °C
• Appearance: /
• Density: 1.32 g/cm³
• Vapor Pressure: 0.00953mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: 2-AMINO-5-(METHYLTHIO)BENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-(METHYLTHIO)BENZOTRIFLUORIDE(59920-85-3)
• EPA Substance Registry System: 2-AMINO-5-(METHYLTHIO)BENZOTRIFLUORIDE(59920-85-3)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 59920-85-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-5-(methylthio)benzotrifluoride is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure contributes to the development of new drugs and medicines, enhancing the range of treatments available for different health conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Amino-5-(methylthio)benzotrifluoride serves as an intermediate in the production of agrochemicals. It plays a crucial role in the synthesis of compounds that are used to protect crops from pests and diseases, thereby contributing to increased agricultural productivity and food security.

InChI:InChI=1/C8H8F3NS/c1-13-5-2-3-7(12)6(4-5)8(9,10)11/h2-4H,12H2,1H3

Upstream product

• 68672-37-7 4-amino-3-(trifluoromethyl)phenyl thiocyanate 
• 75-63-8 Bromotrifluoromethane 
• 104-96-1 4-methylsulfanylaniline 
• 54998-75-3 methyl(4-nitro-3-(trifluoromethyl)phenyl)sulfane 

Relevant articles and documents

Ruthenium-Catalyzed Site-Selective Trifluoromethylations and (Per)Fluoroalkylations of Anilines and Indoles

Introducing (per)fluoroalkyl groups into arenes continues to be an interesting, but challenging area in organofluorine chemistry. We herein report an ortho-selective C?H perfluoroalkylation including trifluoromethylations of anilines and indoles without the need of protecting groups using RfI and RfBr as commercially available reagents. The availability and price of the starting materials and the inherent selectivity make this novel methodology attractive for the synthesis of diverse (per)fluoroalkylated building blocks, for example, for bioactive compounds and materials.

4-Alkylthio-2-trifluoromethylalkanesulfonanilides and derivatives thereof

2-Trifluoromethylalkanesulfonanilides substituted in the para position by alkylthio, alkylsulfinyl or alkylsulfonyl groups and agriculturally acceptable salts thereof are useful herbicides and plant growth regulators.

4-Methylthio-2-trifluoromethylmethanesulfonanilide and derivatives thereof

2-(Trifluoromethyl)methanesulfonanilides substituted in the para position by methylthio, methylsulfinyl or methylsulfonyl groups and horticulturally acceptable salts thereof and composition containing these compounds are useful herbicides.