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59935-31-8

H-[15N]LEU-OH, also known as L-Leucine (15N, 98%), is a stable isotope-labeled amino acid that contains nitrogen-15 (15N) as a tracer. H-[15N]LEU-OH is used in various scientific research applications, particularly in the study of biological processes and metabolic pathways.
Used in Environmental Microbiology Research:
H-[15N]LEU-OH is used as a tracer compound for studying the effect of temperature on the abundance and carbon (C) and nitrogen (N) uptake activity of specific bacterial groups, such as Rhodobacteraceae and Flavobacteria. The use of this stable isotope allows researchers to track and quantify the metabolic activity and preferences of these bacteria under different environmental conditions, providing valuable insights into their ecological roles and potential applications in biotechnology and environmental management.

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  • 59935-31-8 Structure

  • Basic information

    1. Product Name: H-[15N]LEU-OH
    2. Synonyms: [15N]LEUCINE;[15N]-L-LEUCINE;L-LEUCINE-15N;H-[15N]LEU-OH;L-LEUCINE-15N, 98 ATOM % 15N;L-Leucine-15N;[15N]-L-Leucine
    3. CAS NO:59935-31-8
    4. Molecular Formula: C6H13NO2
    5. Molecular Weight: 132.18
    6. EINECS: N/A
    7. Product Categories: Amino Acids 13C, 2H, 15N;I-LMass Spectrometry;Alphabetical Listings;Amino Acids and DerivativesStable Isotopes;Biomolecular MS;Biomolecular NMR;Labeled Amino AcidsStable Isotopes;Products for SILAC;Proteomics Stable Isotope Labeling;Stable Isotopes;Amino Acids;Metabolic Research
    8. Mol File: 59935-31-8.mol

  • Chemical Properties

    1. Melting Point: >300 °C(lit.)
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -15°C
    8. Solubility: Aqueous Acid (Slightly), Water (Slightly)
    9. CAS DataBase Reference: H-[15N]LEU-OH(CAS DataBase Reference)
    10. NIST Chemistry Reference: H-[15N]LEU-OH(59935-31-8)
    11. EPA Substance Registry System: H-[15N]LEU-OH(59935-31-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 59935-31-8(Hazardous Substances Data)

59935-31-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 59935-31-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,9,3 and 5 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 59935-31:
(7*5)+(6*9)+(5*9)+(4*3)+(3*5)+(2*3)+(1*1)=168
168 % 10 = 8
So 59935-31-8 is a valid CAS Registry Number.

59935-31-8 Well-known Company Product Price

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  • Aldrich

  • (340960)  L-Leucine-15N  98 atom % 15N

  • 59935-31-8

  • 340960-500MG

  • 2,589.21CNY

  • Detail

59935-31-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name L-Leucine-15N

1.2 Other means of identification

Product number -
Other names <15N>leucine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:59935-31-8 SDS

59935-31-8Downstream Products

59935-31-8Relevant articles and documents

Stereoselective synthesis of L-[15N] amino acids with glucose dehydrogenase and galactose mutarotase as NADH regenerating system

Chiriac, Maria,Lupan, Iulia,Bucurenci,Popescu,Palibroda

, p. 171 - 174 (2008/09/19)

We have developed an efficient stereospecific enzymatic synthesis of L-[15N]-valine, L-[15N]-leucine, L-[15N]- norvaline, L-[15N]-norleucine and L-[15N]-isoleucine from the corresponding α-keto acids by coupling the reactions catalysed by leucine dehydrogenase and glucose dehydrogenase/galactose mutarotase. Giving high yields of L-amino acids, the procedure is economical and easy to perform and to monitor at a synthetically useful scale (1-10 g). Copyright

Stereoselective synthesis of stable isotope-labeled L-α-amino acids: Electrophilic amination of oppolzer's acyl sultams in the synthesis of L-[15N]alanine, L-[15N]valine, L-[15N]leucine, L-[15N]phenylalanine and

Lodwig,Unkefer

, p. 239 - 248 (2007/10/03)

Using 1-chloro-1-[15N]nitrosocyclohexane, we have prepared five L-[α-15N]amino acids. The stereoselective electophillic hydroxyamination of (S)-acylbornane-10,2-sultams, followed by Zn(o)/H+ reduction, and alkaline cleavag

Chemo-Enzymatic Syntheses of Isotopically Labelled L-Amino Acids

Kelly, Nicholas M.,O'Neill, Bridget C.,Probert, John,Reid, Gordon,Stephen, Rosamund,et al.

, p. 6533 - 6536 (2007/10/02)

L-Alanine labelled with carbon-13 and nitrogen-15 has been prepared in good yield and high optical purity from achiral precursors using alanine dehydrogenase.This versatile approach may be simply adapted for the preparation of a range of isotopically labe

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