600179-41-7Relevant articles and documents
Studies relating to the synthesis, enzymatic reduction and cytotoxicity of a series of nitroaromatic prodrugs
Burke, Philip J.,Wong, Lai Chun,Jenkins, Terence C.,Knox, Richard J.,Meikle, Ian T.,Stanforth, Stephen P.
supporting information, p. 5851 - 5854 (2016/12/06)
A series of N-nitroarylated-3-chloromethyl-1,2,3,4-tetrahydroisoquinoline derivatives, several of which also possessed a trifluoromethyl substituent, were prepared and assessed as potential nitroaromatic prodrugs. The enzymatic reduction of these compound