600179-44-0

Basic information

• Product Name: 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-nitrophenyl)-
• CAS NO: 600179-44-0
• Molecular Formula: C16H14N2O4
• Molecular Weight: 298.298
• Mol File: 600179-44-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-nitrophenyl)-(600179-44-0)
• EPA Substance Registry System: 3-Isoquinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-(2-nitrophenyl)-(600179-44-0)

Safety Data

• Hazardous Substances Data: 600179-44-0(Hazardous Substances Data)

Upstream product

• 67123-97-1 (R,S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 
• 1493-27-2 ortho-nitrofluorobenzene 
• 41994-51-8 1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid ; hydrochloride 

Downstream Products

• 868636-04-8 3-hydroxymethyl-2-(2-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline 
• 868636-02-6 methyl 2-(2-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate 

Relevant articles and documents

Possible neighbouring group participation of a nitro-group in the conversion of 3-hydroxymethyl-2-(2-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline into its 3-chloromethyl derivative

The alcohol 12 reacted with 4-toluenesulfonyl chloride in boiling dichloromethane solution to give the chlorinated product 13 rather than the expected tosylate 3 by a mechanism that could involve neighbouring group participation of the nitro-substituent.