60307-25-7 Usage
General Description
()-1-methyl-5-oxopyrrolidine-2-acetic acid, also known as gabapentin, is a medication primarily used to treat epilepsy and neuropathic pain. It is a derivative of the neurotransmitter gamma-aminobutyric acid (GABA) and works by inhibiting certain calcium channels in the brain, which reduces the release of neurotransmitters involved in pain signaling. Gabapentin is also used off-label to treat anxiety disorders, restless leg syndrome, and hot flashes. It is available in tablet, capsule, and oral solution forms and is generally well-tolerated, with common side effects including dizziness, drowsiness, and weight gain. However, it may also cause serious adverse reactions such as suicidal thoughts, respiratory depression, and allergic reactions. Additionally, it has potential for abuse and dependence and should be used with caution in certain patient populations, such as those with a history of substance abuse.
Check Digit Verification of cas no
The CAS Registry Mumber 60307-25-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,3,0 and 7 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 60307-25:
(7*6)+(6*0)+(5*3)+(4*0)+(3*7)+(2*2)+(1*5)=87
87 % 10 = 7
So 60307-25-7 is a valid CAS Registry Number.
60307-25-7Relevant articles and documents
Construction of Functionalized Azapolycyclic Architectures via Formal Amide Insertion at a Low Catalyst Loading of Copper Trifluoroacetylacetonate
Harada, Shingo,Kato, Ryosuke,Nemoto, Tetsuhiro
, p. 3123 - 3129 (2016/10/09)
A formal amide insertion reaction for the synthesis of nitrogen-bridged polycyclic frameworks with diverse functionalities was developed using a sustainable copper catalyst as an advantageous alternative to precious rhodium catalysts. The remarkable feature of this methodology is the amount of catalyst loading (0.05 mol%). The optimized reaction conditions enable access to aromatic ring-fused 8-azabicyclo[3.2.1]octane, 9-azabicyclo[3.3.1]nonane, and 6-azabicyclo[3.2.2]nonane derivatives in moderate to excellent yields. (Figure presented.).
