60310-07-8Relevant articles and documents
3-OXO-1,4-DIAZEPINYLE COMPOUNDS AS NRF2 ACTIVATORS
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Page/Page column 52, (2018/07/05)
The present invention relates to bisaryl lactam compounds, methods of making them, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the compounds of this invention include a compound of Formula (I):
NRF2 REGULATORS
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Page/Page column 126, (2017/01/02)
Provided are aryl analogs,pharmaceutical compositions containing them and their use as NRF2 regulators.
KAT II INHIBITORS
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Page/Page column 37, (2012/06/16)
The present invention relates to compounds 3-amino-1-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-7-carbonitrile, 3-amino-1-hydxoxy-7-(2-methoxyethoxy)-3,4-dihydro-quinolin-2(1H)-one, and 3-amino-1-hydroxy-7-[(1S)-2-methoxy-1-methylethoxy]-3,4-dihydroquinolin-2(1H)-one, including racemic mixtures and resolved enantiomers thereof, to pharmaceutically acceptable salts thereof, and to the treatment of cognitive deficits associated with schizophrenia and other psychiatric, neurodegenerative and/or neurological disorders in mammals, including humans