606-12-2

Basic information

• Product Name: 2,4'-DIHYDROXYBENZOPHENONE
• Synonyms: Methanone, (2-hydroxyphenyl)(4-hydroxyphenyl)-;(2-Hydroxyphenyl)(4-hydroxyphenyl)methanone
• CAS NO: 606-12-2
• Molecular Formula: C₁₃H₁₀O₃
• Molecular Weight: 214.22
• Mol File: 606-12-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 146.0 to 150.0 °C
• Boiling Point: 383.6 °C at 760 mmHg
• Flash Point: 200 °C
• Appearance: /
• Density: 1.302 g/cm³
• Vapor Pressure: 1.97E-06mmHg at 25°C
• Refractive Index: 1.647
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.65±0.15(Predicted)
• CAS DataBase Reference: 2,4'-DIHYDROXYBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4'-DIHYDROXYBENZOPHENONE(606-12-2)
• EPA Substance Registry System: 2,4'-DIHYDROXYBENZOPHENONE(606-12-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 606-12-2(Hazardous Substances Data)

Usage

Uses

2,4''-Dihydroxybenzophenone is used in preparation method of anti-fog and antibacterial coating of nanocomposite material.

Preparation

Preparation by diazotization of 2,4′ -diamino- 2′,4-di-hydroxybenzophenone, followed by decomposition of the diazonium salt obtained in the presence of 50% hypo-phosphorous acid (57%).

InChI:InChI=1/C13H10O3/c14-10-7-5-9(6-8-10)13(16)11-3-1-2-4-12(11)15/h1-8,14-15H

Upstream product

• 959033-36-4 (2-acetoxy-phenyl)-(4-acetoxy-phenyl)-methane 
• 118-55-8 phenyl Salicylate 
• 69-72-7 salicylic acid 
• 108-95-2 phenol 
• 56-23-5 tetrachloromethane 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 113272-16-5 (1α,4aβ,9aβ)-1,2,4a,9a-tetrahydro-1-methoxy-3,9-dioxo-4H-xanthene-9a-carboxaldehyde 
• 113272-11-0 (8aR,10aR)-8-Methoxy-9-oxo-6-trimethylsilanyloxy-5,10a-dihydro-8H,9H-xanthene-8a-carbaldehyde 
• 7646-78-8 tin(IV) chloride 
• 7446-70-0 aluminium trichloride 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 71-43-2 benzene 
• 5449-69-4 2,4'-dimethoxybenzophenone 
• 10035-10-6 hydrogen bromide 

Downstream Products

• 108-95-2 phenol 
• 99-96-7 4-hydroxy-benzoic acid 
• 5449-69-4 2,4'-dimethoxybenzophenone 
• 433331-38-5 4-allyloxy-2'-hydroxybenzophenone 
• 1353010-66-8 (4'-ethylbiphenyl-4-yl)(4'-vinylbiphenyl-2-yl)methanone 
• 1353010-65-7 (3',5'-dimethylbiphenyl-4-yl)(4'-vinylbiphenyl-2-yl)methanone 
• 1353010-64-6 (4'-tert-butylbiphenyl-4-yl)(4'-vinylbiphenyl-2-yl)methanone 

Relevant articles and documents

Selective Oxidation of Alkylarenes to the Aromatic Ketones or Benzaldehydes with Water

Here a palladium-catalyzed oxidation method for converting alkylarenes into the aromatic ketones or benzaldehydes with water as the only oxygen donor is reported. This C-H bond oxidation functionalization does not require other oxidants and hydrogen accep

Cycloadditions of substituted benzopyran-4-ones to electron-rich dienes: a new route to xanthone derivatives

The benzopyranones 1 and 3 reacted with 2,3-dimethyl-1,3-butadiene in the presence of titanium (IV) chloride to give the corresponding (4 + 2) cycloadducts 8 and 11, the former undergoing facile deformylation to give 9 and 10. Compounds 1, 3, and 4 underwent efficient uncatalysed cycloaddition to 1- methoxy-3-(trimethylsilyloxy)-l,3-butadiene 12 to give the respective adducts 13,14, and 18 as mixtures of C-l stereoisomers. Heating the 3-arylsulphinylchromone 5 with the diene 12 afforded 3-hydroxyxanthone 23 in 50% yield, the presumed cycloaddition - elimination sequence constituting a new route to xanthone systems. Desilylation of 13,14, and 18 in acidic media provided 25,26, and 27 respectively.