614-72-2

Basic information

• Product Name: 2-CHLOROPHENETOLE
• Synonyms: 2-CHLOROPHENETOLE;1-CHLORO-2-ETHOXYBENZENE;O-CHLOROETHOXYBENZENE;O-CHLOROPHENETOLE;2-Chlorophenol ethyl ether;2-chlorophenolethylether;Benzene, 1-chloro-2-ethoxy-;benzene,1-chloro-2-ethoxy-
• CAS NO: 614-72-2
• Molecular Formula: C₈H₉ClO
• Molecular Weight: 156.61
• EINECS: 210-392-7
• Product Categories: Phenetole
• Mol File: 614-72-2.mol
• Article Data: 7

Chemical Properties

• Melting Point: 190-191.5 °C
• Boiling Point: 210 °C
• Flash Point: 82.3 °C
• Appearance: /
• Density: 1,14 g/cm3
• Refractive Index: 1.5290-1.5320
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLOROPHENETOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLOROPHENETOLE(614-72-2)
• EPA Substance Registry System: 2-CHLOROPHENETOLE(614-72-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 614-72-2(Hazardous Substances Data)

Usage

General Description

2-Chlorophenetole is an organic compound that consists of a phenyl ring with a chlorine atom and a methoxy group attached to it. Also known as 2-chloroanisole, it is commonly used in the fragrance industry as a synthetic aroma compound with a sweet, floral odor. It is also found in some essential oils and natural plant extracts. 2-Chlorophenetole is used in the production of perfumes, soaps, and other scented products, and also serves as an intermediate in the synthesis of various pharmaceuticals and other organic compounds. It is a clear, colorless liquid with a slightly sweet aroma, and it is considered to be relatively stable and non-reactive under normal conditions. However, it should be handled with care and stored in a cool, dry place.

InChI:InChI=1/C8H9ClO/c1-2-10-8-6-4-3-5-7(8)9/h3-6H,2H2,1H3

Upstream product

• 95-57-8 2-monochlorophenol 
• 94-70-2 ortho-phenitidine 
• 64-17-5 ethanol 
• 95-50-1 1,2-dichloro-benzene 
• 103-73-1 Phenetole 
• 64-67-5 diethyl sulfate 
• 64-19-7 acetic acid 
• 7647-01-0 hydrogenchloride 
• 95-51-2 o-chloroaniline 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 1193-00-6 sodium 4-chlorophenolate 

Downstream Products

• 105475-82-9 4-(4-ethoxy-3-chloro-phenyl)-4-oxo-butyric acid 
• 37612-59-2 1-(4-ethoxy-3-chloro-phenyl)-ethanone 
• 83493-63-4 2-(4-ethoxyphenyl)-2,2-dimethylethanol 
• 95-57-8 2-monochlorophenol 
• 13519-73-8 2-ethoxy-N-ethylaniline 
• 103-73-1 Phenetole 
• 87067-16-1 2-chloro-4-(1-chloro-2-methylpropan-2-yl)-1-ethoxybenzene 
• 854867-59-7 2-(4-ethoxy-3-chloro-phenyl)-quinoline-4-carboxylic acid 

Relevant articles and documents

PARA-PREFERENTIAL ANODIC CHLORINATION OF ALKOXYBENZENES

Anodic chlorination of methoxy- and ethoxybenzenes yielded p-alkoxychlorobenzenes preferentially.The p-/o- ratios were 34.5 in N,N-dimethylacetamide-LiCl and 17.1 in N,N-dimethylformamide-LiCl.In the former case, the current efficiency for producing p-chloromethoxybenzene was 95.8percent at Pt anode.

Facile Synthesis of Chloro-substituted Aromatic Ethers by Use of Benzyltrimethylammonium Tetrachloroiodate

The reaction of aromatic ethers with a calculated amount of benzyltrimethylammonium tetrachloroiodate in acetic acid (or dichloromethane) under mild conditions gave, selectively, the objective chloro-substituted aromatic ethers in good yields.

Process for producing 3-phenoxybenzyl 2-(4-alkoxyphenyl)-2-methylpropyl ethers

The present invention relates to a process for producing 3-phenoxybenzyl 2-(4-alkoxyphenyl)-2-methylpropyl ethers having excellent insecticidal and acaricidal activities which are represented by formula (IV): STR1 wherein R is a lower alkyl group and X1 and X2 are each a hydrogen or fluorine atom, which comprises reacting a 3-halogeno-4-alkoxyneophyl halide represented by the formula (I): STR2 wherein Y1 and Y2 are each a hydrogen, chlorine or bromine atom, at least one of them being a chlorine or bromine atom, R has the same meaning as above and X is a halogen atom, with a 3-phenoxybenzyl alcohol represented by the formula (II): STR3 wherein X1 and X2 have the same meaning as above, in the presence of a base to obtain a 3-phenoxybenzyl 2-(4-alkoxy-3-halogenophenyl)-2-methylpropyl ether represented by the formula (III): STR4 wherein Y1, Y2, R, X1 and X2 have the same meaning as above, and then subjecting the product to a hydrodehalogenation reaction, and relates to a process for producing a 3-halogeno-4-alkoxyneophyl halide represented by formula (I), which comprises reacting a 2-halogeno-1-alkoxybenzene represented by formula (V): STR5 wherein Y1 and Y2 are each a hydrogen, chlorine or bromine atom, at least one of them being a chlorine or bromine atom, and R represents a lower alkyl group, with a methallyl halide in the presence of an acid catalyst at -20° to 50° C.