61428-20-4

Basic information

• Product Name: 3-(4-METHOXYPHENYL)ISOXAZOLE
• Synonyms: 3-(4-METHOXYPHENYL)ISOXAZOLE
• CAS NO: 61428-20-4
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.18
• Mol File: 61428-20-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 51-53°C
• Boiling Point: 319.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.132±0.06 g/cm3(Predicted)
• PKA: -2.49±0.50(Predicted)
• CAS DataBase Reference: 3-(4-METHOXYPHENYL)ISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-METHOXYPHENYL)ISOXAZOLE(61428-20-4)
• EPA Substance Registry System: 3-(4-METHOXYPHENYL)ISOXAZOLE(61428-20-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 61428-20-4(Hazardous Substances Data)

Usage

General Description

3-(4-Methoxyphenyl)isoxazole is a chemical compound with the molecular formula C10H9NO2. It is a derivative of isoxazole, a five-membered heterocyclic ring containing one oxygen and one nitrogen atom. The compound consists of a isoxazole ring with a 4-methoxyphenyl group attached to the third position. 3-(4-Methoxyphenyl)isoxazole is commonly used as a building block in organic synthesis and medicinal chemistry, and its derivatives have been studied for their potential pharmacological activities, including as anti-inflammatory and analgesic agents. Additionally, this compound has also been investigated for its potential role in the treatment of neurological disorders.

Upstream product

• 947-57-9 dimethyl bicyclo[2.2.1]hept-2,5-diene-2,3-dicarboxylate 
• 15500-73-9 4-methoxybenzonitrile oxide 
• 19019-88-6 7-isopropylidene-2,3-dicarbomethoxynorbornadiene 
• 35167-28-3 vinyl phenyl selenide 
• 20451-53-0 Phenyl vinyl sulfoxide 
• 38435-51-7 N-hydroxy-4-methoxy-benzenecarboximidoyl chloride 
• 3717-21-3 p-methoxyl benzaldoxime 
• 1963-36-6 4-methoxycinnamaldehyde 
• 37614-59-8 4-(4-methoxyphenyl)prop-2-yn-1-ol 
• 92409-23-9 3-hydroxy-2-(2-methoxyphenoxy)-1-(4-methoxyphenyl)propan-1-one 
• 18096-70-3 3-dimethylamino-4'-methoxyacrylophenone 
• 1829-60-3 dimethyl 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate 
• 61428-15-7 3-(4-methoxy-phenyl)-5-nitro-4,5-dihydro-isoxazole 

Downstream Products

• 874-90-8 4-methoxybenzonitrile 
• 33064-24-3 5-(4-methoxyphenyl)-1-phenyl-1H-pyrazole 
• 33064-21-0 3-(4-methoxy-phenyl)-1-phenyl-1H-pyrazole 

Relevant articles and documents

Preparation method of isoxazole derivative

The invention relates to a preparation method of an isoxazole derivative, which comprises the following steps of mixing an propargyl alcohol derivative, a halogen source, an acid and a solvent, and heating to react; adding the hydroxylamine into the react

Polymer-supported vinyl sulfone as an efficient reagent for the synthesis of 3-monosubstituted isoxazoles

Polystyrene-supported vinyl sulfone reagent has been developed and used for solid-phase organic synthesis of 3-monosubstituted isoxazoles by 1,3-dipolar cycloaddition reaction with nitrile oxides and subsequent cleavage from the polymer support through an

Reaction of β-dimethylaminovinyl ketones with hydroxylamine: A simple and useful method for synthesis of 3- and 5-substituted isoxazoles

(Chemical Equation Presented) The regioselective synthesis of 3- and 5-substituted-isoxazoles from the reaction of β-dimethylaminovinyl ketones [R-C(O)CH=CH-NMe2, where R = Ph, MeO-4-C6H4, F-4-C6H4, C