6158-45-8

Basic information

• Product Name: 1-ISOPROPYLNAPHTHALENE
• Synonyms: 1-(1-methylethyl)-naphthalen;1-(1-methylethyl)naphthalene;alpha-Isopropylnaphthalene;Naphthalene, 1-isopropyl-;naphthalene,1-(1-methylethyl)-;1-ISOPROPYLNAPHTHALENE
• CAS NO: 6158-45-8
• Molecular Formula: C₁₃H₁₄
• Molecular Weight: 170.25
• EINECS: 228-177-1
• Mol File: 6158-45-8.mol
• Article Data: 35

Chemical Properties

• Melting Point: -16°C(lit.)
• Boiling Point: 268 °C
• Appearance: /
• Density: 0,99 g/cm3
• Refractive Index: 1.5920-1.5950
• Storage Temp.: 0-10°C
• CAS DataBase Reference: 1-ISOPROPYLNAPHTHALENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ISOPROPYLNAPHTHALENE(6158-45-8)
• EPA Substance Registry System: 1-ISOPROPYLNAPHTHALENE(6158-45-8)

Safety Data

• Safety Statements: 23-24/25
• Hazardous Substances Data: 6158-45-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron, 31, p. 153, 1975 DOI: 10.1016/0040-4020(75)85010-1

InChI:InChI=1S/C13H14/c1-10(2)12-9-5-7-11-6-3-4-8-13(11)12/h3-10H,1-2H3

Upstream product

• 91-20-3 naphthalene 
• 2307-69-9 toluene-4-sulfonic acid isopropyl ester 
• 1855-47-6 1-(propen-2-yl)naphthalene 
• 6301-54-8 2-(naphthalen-1-yl)propan-2-ol 
• 67-63-0 isopropyl alcohol 
• 703-55-9 1-naphthylmagnesiumbromide 
• 75-29-6 isopropyl chloride 
• 807329-97-1 TurboGrignard 
• 68211-49-4 1-naphthyl tosylate 
• 321-38-0 1-Fluoronaphthalene 
• 1068-55-9 isopropylmagnesium chloride 
• 920-39-8 isopropylmagnesium bromide 
• 80041-89-0 isopropylboronic acid 
• 99747-74-7 1-naphthyl triflate 

Downstream Products

• 16712-64-4 6-Hydroxy-2-naphthoic acid 
• 1855-47-6 1-(propen-2-yl)naphthalene 
• 2027-17-0 2-Isopropylnaphthalene 
• 24157-81-1 2,6-diisopropylnaphthalene 
• 40458-98-8 2,7-diisopropylnaphthalene 
• 57122-16-4 1,3-diisopropylnaphthalene 
• 860596-08-3 2-(4-isopropyl-[1]naphthoyl)-benzoic acid 
• 6301-54-8 2-(naphthalen-1-yl)propan-2-ol 
• 69736-23-8 4-naphthalen-1-yl-[1,2]dithiole-3-thione 

Relevant articles and documents

METHOD FOR PRODUCING ARENE COMPOUNDS AND ARENE COMPOUNDS PRODUCED BY THE SAME

Provided is a method for producing (alkyl)arene compounds represented by Formulae 3-1, 3-2, and 3-3 by the Friedel-Crafts alkylation reaction of alkyl halide compounds and arene compounds using organic phosphine compounds as a catalyst.

Efficient Pd-Catalyzed Direct Coupling of Aryl Chlorides with Alkyllithium Reagents

Organolithium compounds are amongst the most important organometallic reagents and frequently used in difficult metallation reactions. However, their direct use in the formation of C?C bonds is less established. Although remarkable advances in the coupling of aryllithium compounds have been achieved, Csp2?Csp3 coupling reactions are very limited. Herein, we report the first general protocol for the coupling or aryl chlorides with alkyllithium reagents. Palladium catalysts based on ylide-substituted phosphines (YPhos) were found to be excellently suited for this transformation giving high selectivities at room temperature with a variety of aryl chlorides without the need for an additional transmetallation reagent. This is demonstrated in gram-scale synthesis including building blocks for materials chemistry and pharmaceutical industry. Furthermore, the direct coupling of aryllithiums as well as Grignard reagents with aryl chlorides was also easily accomplished at room temperature.

Bioinspired Metal-Free Formal Decarbonylation of α-Branched Aliphatic Aldehydes at Ambient Temperature

A sequence of a Baeyer–Villiger oxidation and a Lewis acid-promoted reduction of the resulting formate with Et3SiH enabled the metal-free formal decarbonylation of tertiary and secondary aliphatic aldehydes. The new methodology mimics the biosynthetic decarbonylation pathway through oxidative C?C bond cleavage rather than the C(O)?H bond activation known from conventional Tsuji–Wilkinson-type reactions. The substrate scope is complementary to existing transition-metal-catalyzed protocols.