616-09-1

Basic information

• Product Name: ISOPROPYL (S)-(-)-LACTATE
• Synonyms: ISOPROPYL-S(-)-2-HYDROXY-PROPIONATE;ISOPROPYL (S)-(-)-LACTATE;ISOPROPYL-(S)-LACTATE;ISOPROPYL ESTER OF NATURAL L(+)- LACTIC ACID;ISOPROPYL LACTATE;(-)-ISOPROPYL L-LACTATE;LACTIC ACID N-PROPYL ESTER;L(+) LACTIC ACID, ISOPROPYL ESTER
• CAS NO: 616-09-1
• Molecular Formula: C₆H₁₂O₃
• Molecular Weight: 132.16
• EINECS: 264-417-1
• Mol File: 616-09-1.mol
• Article Data: 23

Chemical Properties

• Melting Point: 1 °C
• Boiling Point: 166-168 °C(lit.)
• Flash Point: 135 °F
• Appearance: /
• Density: 0.988 g/mL at 25 °C(lit.)
• Vapor Density: 4.2 (vs air)
• Vapor Pressure: 0.38mmHg at 25°C
• Refractive Index: n20/D 1.411(lit.)
• PKA: 13.06±0.20(Predicted)
• Water Solubility: Completely miscible in water
• Stability: Incompatible with strong oxidizing agents.
• CAS DataBase Reference: ISOPROPYL (S)-(-)-LACTATE(CAS DataBase Reference)
• NIST Chemistry Reference: ISOPROPYL (S)-(-)-LACTATE(616-09-1)
• EPA Substance Registry System: ISOPROPYL (S)-(-)-LACTATE(616-09-1)

Safety Data

• Statements: 10
• Safety Statements: 23-24/25
• RIDADR: UN 3272 3/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 616-09-1(Hazardous Substances Data)

Usage

General Description

ISOPROPYL (S)-(-)-LACTATE is a chemical compound with the molecular formula C6H12O3. It is an isomer of isopropyl lactate, with a specific rotation of -1.3 degrees. ISOPROPYL (S)-(-)-LACTATE is commonly used as a solvent in various applications, including in the manufacturing of pharmaceuticals, fragrances, and cosmetics. It is also used as a flavoring agent and as an intermediate in the production of other chemicals. ISOPROPYL (S)-(-)-LACTATE is known for its low toxicity and high solvency power, making it a versatile ingredient in a range of industrial and consumer products.

InChI:InChI=1/C6H12O3/c1-3-4-9-6(8)5(2)7/h5,7H,3-4H2,1-2H3

Upstream product

• 71-23-8 propan-1-ol 
• 849585-22-4 LACTIC ACID 
• 547-64-8 methyl lactate 
• 312-85-6 sodium lactate 
• 814-80-2 calcium lactate 
• 79-33-4 L-Lactic acid 
• 96-26-4 dihydroxyacetone 
• 57-50-1 Sucrose 
• 20279-43-0 n-propyl pyruvate 
• 107-08-4 1-iodo-propane 
• 13076-17-0 D-lactide 
• 6819-41-6 sodium n-propoxide 
• 78-98-8 2-oxopropanal 
• 97-64-3 ethyl 2-hydroxypropionate 

Downstream Products

• 20473-73-8 2-acetoxy-propionic acid propyl ester 
• 849585-22-4 LACTIC ACID 
• 27871-49-4 (S)-Methyl lactate 
• 17392-83-5 (R)-Methyl lactate 
• 5334-85-0 diethylene glycol-O.O-dicarboxylic acid bis-(1-carbopropyloxy-ethyl ester) 

Relevant articles and documents

METHOD FOR PREPARING ALKYL HYDROXYL ACID ESTER AND USE THEREOF

Provided is a method for preparing an alkyl hydroxyl acid ester, the product and use thereof. The method has advantages of high yield, not producing waste water, gas, or solid, low cost, and is green and environment friendly.

Preparation method and application of hydroxy acid alkyl ester

The invention relates to a preparation method of a green solvent hydroxy acid alkyl ester, which comprises the following steps: (1) an alkyl alcohol and a hydroxy acid methyl ester or an ethyl ester are mixed under normal pressure or micro-positive pressure in the presence of a catalyst and reacted at the temperature of 50-200 DEG C, and the molar ratio of alkyl alcohol to the hydroxy acid methylester or ethyl ester is greater than 1; (2) at the temperature of 135-170 DEG C, a product methanol or ethanol is fractionated for the first time, and the top temperature of a fractionating column isthe boiling point temperature of methanol or ethanol; (3) atmospheric pressure or reduced pressure distillation is carried out for the second time to obtain redundant reactants alkyl alcohol and unreacted hydroxy acid methyl ester or ethyl ester, and the distillation temperature is controlled to be the boiling point temperature of the alkyl alcohol and the hydroxy acid methyl ester or ethyl ester;and (4) the remaining product hydroxy acid alkyl ester is collected. The method has the advantages of high yield, no generation of any three wastes, low production cost, greenness and environmental protection.

Retention Characteristics and Sorption Enthalpies of Esters of Natural Hydroxycarboxylic Acids on DB-1 Stationary Phase

Abstract: Sorption characteristics and retention of esters of glycolic, lactic, malic, and tartaric acids with C1?C8 alcohols of linear structure are studied by gas-liquid chromatography in the temperature range of 90?260°C on DB-1 nonpolar phase. The values of the retention indices of the compounds studied are obtained. On the basis of experimentally determined retention times, the thermodynamic characteristics of sorption under the conditions of limiting dilution are estimated. The dependences of the change in sorption enthalpies on the length of the linear alkyl substituent and on the value of the logarithmic retention index are found. The possibility of estimating the energy of intermolecular interactions of lactic acid esters in the liquid phase is shown on the basis of the obtained values of sorption enthalpies and vaporization enthalpies.