620960-26-1Relevant articles and documents
Enantioselective construction of quaternary carbon centre catalysed by bifunctional organocatalyst
Liu, Tian-Yu,Long, Jun,Li, Bang-Jing,Jiang, Lin,Li, Rui,Wu, Yong,Ding, Li-Sheng,Chen, Ying-Chun
, p. 2097 - 2099 (2006)
A highly efficient organocatalytic method for the asymmetric Michael addition of α-substituted cyanoacetates to vinyl sulfones was investigated. It was observed that this reaction was synergistically promoted by readily available bifunctional thiourea-ter
A simplified synthesis of Takemoto's catalyst
Berkessel,Seelig
, p. 2113 - 2115 (2009)
A facile two-step procedure for the preparation of Takemoto's catalyst is reported. The thiourea moiety was obtained by condensation of 3,5-bis(trifluoromethyl)aniline with phenyl chlorothioformate and in situ substitution of phenol by trans-1,2-diaminocy
Thiocarbonyl Surrogate via Combination of Sulfur and Chloroform for Thiocarbamide and Oxazolidinethione Construction
Tan, Wei,Wei, Jianpeng,Jiang, Xuefeng
supporting information, p. 2166 - 2169 (2017/04/27)
An efficient and practical thiocarbonyl surrogate via combination of sulfur and chloroform has been developed. A variety of thiocarbamides and oxazolidinethiones have been established, including chiral thiourea catalysts and chiral oxazolidinethione auxiliaries with high selectivity. Meanwhile, pesticides Diafenthiuron (an acaricide), ANTU (a rodenticide), and Chloromethiuron (an insecticide) were practically synthesized through this method in gram scale. Dicholorocarbene, as the key intermediate, was further confirmed via a carbene-trapping control experiment.
Asymmetric isomerization of ω-hydroxy-α,β-unsaturated thioesters into β-mercaptolactones by a bifunctional aminothiourea catalyst
Fukata, Yukihiro,Okamura, Takaaki,Asano, Keisuke,Matsubara, Seijiro
, p. 2184 - 2187 (2014/05/06)
We present a novel methodology for the asymmetric synthesis of β-mercaptolactones via isomerization of ω-hydroxy-α,β- unsaturated thioesters by means of a bifunctional aminothiourea catalyst. The catalyst interacts with the substrate through the cooperati