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62253-63-8

Epidermal Growth Factor (EGF) is a protein that plays a crucial role in cell growth, proliferation, and differentiation. It is found in various human and animal tissues and has been widely used in medical and cosmetic applications due to its ability to stimulate healing and regeneration.
Used in Ophthalmology:
Epidermal Growth Factor is used as a supplement in ophthalmic formulations for the stimulation of healing of the corneal epithelium following various corneal diseases.
Used in Cell Culture:
Epidermal Growth Factor is used as a supplement in LHC-8 medium to culture liver cell lines in the fetal bovine serum (FBS)-Dulbecco's modified essential medium (DMEM)/F12 medium for primary culture of human glioma cells.
Used in Cancer Research:
Epidermal Growth Factor is used as an additive in the conditional medium of normal fibroblasts (NFs) to study its effect on the migration and invasion of endometrial cancer (EC) cells.
Used in Tumorsphere Medium:
Epidermal Growth Factor is used as a component in tumorsphere medium, which is a specialized culture medium designed to support the growth and maintenance of cancer stem cells.
Used in Mammary Epithelial Cell Culture:
EGF (epidermal growth factor) human has been used in the culture medium for the maintenance of MCF10A cells (human mammary epithelial cells).
Used in Tissue Culture:
This product is used as a mitogen, triggering the cell to commence mitosis, in a variety of cell lines. In tissue cultures, EGF acts to reduce or eliminate the requirement for serum and can be used in conjunction with other media additives and hormones.

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  • 62253-63-8 Structure

  • Basic information

    1. Product Name: Epidermal Growth Factor
    2. Synonyms: RECOMBINANT MOUSE EGF;RECOMBINANT HUMAN EGF;REC EPIDERMAL GROWTH FACTOR (HUMAN);REC EGF (HUMAN);RHEGF;MURINE URG;MURINE UROGASTRONE;MOUSE EGF
    3. CAS NO:62253-63-8
    4. Molecular Formula: C270H401N73O83S7
    5. Molecular Weight: 6221.96724
    6. EINECS: 263-468-7
    7. Product Categories: Cytokine
    8. Mol File: 62253-63-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Epidermal Growth Factor(CAS DataBase Reference)
    10. NIST Chemistry Reference: Epidermal Growth Factor(62253-63-8)
    11. EPA Substance Registry System: Epidermal Growth Factor(62253-63-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS: KB4518000
    6. F: 10-21
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 62253-63-8(Hazardous Substances Data)

62253-63-8 Usage

Originator

Inpharzam (Italy)

Biochem/physiol Actions

Epidermal growth factor (EGF) helps to induce cell growth, proliferation and differentiation. It participates in the repairing of renal tissues in the kidney. It promotes the reabsorption of magnesium with the help of the transient receptor potential cation channel 6 (TRMP6). EGF is known to participate in the pathophysiology of drug-induced renal magnesium loss.

Check Digit Verification of cas no

The CAS Registry Mumber 62253-63-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,2,5 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 62253-63:
(7*6)+(6*2)+(5*2)+(4*5)+(3*3)+(2*6)+(1*3)=108
108 % 10 = 8
So 62253-63-8 is a valid CAS Registry Number.

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