624-73-7

Basic information

• Product Name: 1,2-DIIODOETHANE
• Synonyms: 1,2-DIIODOETHANE;ETHYLENE DIIODIDE;ETHYLENE IODIDE;1,2-Diiodoethane,98%;1,2-Diiodoethane, GC 99%;Ethylene diiodide, Ethylene iodide;1,2-Diiodoethane,99%;1,2-Diiodoethane ,98.5%
• CAS NO: 624-73-7
• Molecular Formula: C₂H₄I₂
• Molecular Weight: 281.86
• EINECS: 210-859-5
• Product Categories: Alkyl;Building Blocks;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 624-73-7.mol
• Article Data: 8

Chemical Properties

• Melting Point: 80-82 °C(lit.)
• Boiling Point: 200.05°C
• Flash Point: 100.9 °C
• Appearance: Light brown to brown/Crystals or Crystalline Powder
• Density: 2.132 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.349mmHg at 25°C
• Refractive Index: 1.8710
• Storage Temp.: 2-8°C
• Water Solubility: Soluble in methanol. Insoluble in water.
• Sensitive: Air & Light Sensitive
• Stability: Stable, but may discolour on exposure to light. Incompatible with strong bases, strong oxidizing agents.
• BRN: 1730870
• CAS DataBase Reference: 1,2-DIIODOETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIIODOETHANE(624-73-7)
• EPA Substance Registry System: 1,2-DIIODOETHANE(624-73-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• RIDADR: 2811
• WGK Germany: 3
• F: 8-9-23
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 624-73-7(Hazardous Substances Data)

Usage

Chemical Properties

dark brown crystals

Uses

Different sources of media describe the Uses of 624-73-7 differently. You can refer to the following data:
1. 1,2-Diiodoethane is used as C-X bond formation reagent. It is also used as Pharmaceutical intermediates.
2. 1,2-Diiodoethane can be used:To synthesize samarium(II) iodide-water complex (SmI2-H2O complex), a single-electron transfer reagent, to further synthesize 3-hydroxy carboxylic acids.To synthesize derivatives of regioselective homopropargyl alcohols by using sonochemical Barbier-type reaction conditions.As an iodine source and an effective reagent for the dehydroxy-iodination of alcohols.

Purification Methods

Dissolve it in ether, wash it with saturated aqueous Na2S2O3, dry over MgSO4 and evaporate the ether in vacuo and distil it. Store it in the dark. [Molander et al. J Am Chem Soc 109 453 1987]. [Beilstein 1 IV 169.]

InChI:InChI=1/C2H4I2/c3-1-2-4/h1-2H2

Upstream product

• 123-91-1 1,4-dioxane 
• 67-64-1 acetone 
• 74-88-4 methyl iodide 
• 506-78-5 cyanogen iodide 
• 74-85-1 ethene 
• 74-86-2 acetylene 
• 10034-85-2 hydrogen iodide 
• 7790-99-0 iodine monochloride 
• 7790-99-0 α-iodomonochloride 
• 107-21-1 ethylene glycol 
• 7790-99-0 Iodine monochloride 
• 7732-18-5 water 
• 7553-56-2 iodine 
• 111-46-6 diethylene glycol 

Downstream Products

• 100-71-0 2-Ethylpyridine 
• 536-75-4 4-Ethylpyridine 
• 6069-06-3 2-iodoethyl ethyl ether 
• 111-55-7 ethylene glycol diacetate 
• 75-21-8 oxirane 
• 74-85-1 ethene 
• 762-51-6 1-fluoro-2-iodoethane 
• 2366-52-1 1-fluorobutane 
• 593-66-8 vinyliodide 
• 7570-26-5 1,2-dinitroethane 
• 138942-63-9 C₈₈H₆₂N₁₀⁽²⁺⁾*2I^(1-) 
• 107-01-7 butene-2 
• 590-19-2 2,3-dimethylbutene 
• 624-72-6 1,2-difluoroethane 

Relevant articles and documents

Carbodeoxygenation of biomass: The carbonylation of glycerol and higher polyols to monocarboxylic acids

Glycerol is converted to a mixture of butyric and isobutyric acid by rhodium- or iridium-catalysed carbonylation using HI as the co-catalyst. The initial reaction of glycerol with HI results in several intermediates that lead to isopropyl iodide, which upon carbonylation forms butyric and isobutyric acid. At low HI concentration, the intermediate allyl iodide undergoes carbonylation to give vinyl acetic acid and crotonic acid. Higher polyols CnH n+2(OH)n are carbonylated to the corresponding C n+1 mono-carboxylic acids. Copyright

Reactions of trimethyliodosilane with mono-, di-, and trioxacycloalkanes

The reactions of Me3SiI with mono-, di-, and trioxacycloalkanes have been studied first.Preparative methods for the synthesis of some promising synthones, namely α,ω-diiodoalkanes, α,ω-alkanediols, and iodomethyl ω-iodoalkyl ethers, have been developed based on these reactions.The effect of the cycle size and the nature of the substituent on the course of the reactions is demonstrated.Schemes for the mechanism of the reactions are suggested.

vic-Iodo Thiocyanates and Iodo Isothiocyanates. IX A Synthesis of Penam and Other Polycyclic β-Lactams

Penam (4-thia-1-azabicycloheptan-7-one) and 2,3-disubstituted penams are prepared conveniently from vic-iodo isothiocyanates beginning with the facile cyclization of the latter with di-t-butyl sodiomalonates.Treatment of the resulting di-t-butyl 2-(thiazolidin-2-ylene)malonates with trifluoroacetic acid gives t-butyl 2-thiazolin-2-ylacetate derivatives which are reduced to the corresponding thiazolidines with aluminium amalgam.Cleavage of these t-butyl esters with hydrogen chloride affords β-amino acid hydrochlorides, which are cyclized to penam and its derivatives with 1--3-ethylcarbodiimide hydrochloride.The structures of the (2α,3aβ,7aβ)-thiazolidine (5) and of the tricyclic β-lactam (41) have been confirmed by X-ray crystallography.