626605-09-2Relevant articles and documents
Design, synthesis, and biological evaluation of novel 7-azaindolyl- heteroaryl-maleimides as potent and selective glycogen synthase kinase-3β (GSK-3β) inhibitors
O'Neill, David J.,Shen, Lan,Prouty, Catherine,Conway, Bruce R.,Westover, Lori,Xu, Jun Z.,Zhang, Han-Cheng,Maryanoff, Bruce E.,Murray, William V.,Demarest, Keith T.,Kuo, Gee-Hong
, p. 3167 - 3185 (2007/10/03)
Two approaches were developed to synthesize the novel 7-azaindolyl- heteroarylmaleimides. The first approach was based upon the palladium-catalyzed Suzuki cross-coupling or Stille cross-coupling of 2-chloro-maleimide 5 with various arylboronic acids or ar