6278-04-2

Basic information

• Product Name: 1-(PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL
• Synonyms: 1-(PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL
• CAS NO: 6278-04-2
• Molecular Formula: C₂₂H₂₃NO
• Molecular Weight: 317.4241
• Mol File: 6278-04-2.mol
• Article Data: 33

Chemical Properties

• Boiling Point: 471°Cat760mmHg
• Flash Point: 234.2°C
• Appearance: /
• Density: 1.166g/cm³
• Vapor Pressure: 1.71E-09mmHg at 25°C
• Refractive Index: 1.655
• CAS DataBase Reference: 1-(PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL(6278-04-2)
• EPA Substance Registry System: 1-(PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL(6278-04-2)

Safety Data

• Hazardous Substances Data: 6278-04-2(Hazardous Substances Data)

Usage

General Description

1-(Phenyl(piperidin-1-yl)methyl)naphthalen-2-ol, also known as NAPPI, is a chemical compound with a complex structure. It is an organic compound that contains a phenyl group, a piperidine ring, and a naphthalen-2-ol moiety. 1-(PHENYL(PIPERIDIN-1-YL)METHYL)NAPHTHALEN-2-OL is commonly used as a building block in the synthesis of a wide range of pharmaceuticals, agrochemicals, and other biologically active molecules. It has shown potential as a ligand for various receptors and enzymes and has been studied for its potential use in the treatment of various medical conditions. The compound's unique structural features make it a versatile building block for the design and synthesis of diverse bioactive compounds.

InChI:InChI=1/C22H23NO/c24-20-14-13-17-9-5-6-12-19(17)21(20)22(18-10-3-1-4-11-18)23-15-7-2-8-16-23/h1,3-6,9-14,22,24H,2,7-8,15-16H2

Upstream product

• 2538-76-3 1,1'-benzylidenedipiperidine 
• 135-19-3 β-naphthol 
• 121238-80-0 N-<α-(benzotriazol-1-yl)phenylmethyl>piperidine 
• 875-83-2 sodium 2-naphtholate 
• 3768-56-7 1-(trimethylsilyl)piperidine 
• 110-89-4 piperidine 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 
• 98-80-6 phenylboronic acid 
• 100-52-7 benzaldehyde 
• 530-93-8 1,2,3,4-tetrahydronaphthalen-2-one 
• 502618-02-2 (E)-1-benzylidene-3,4-dihydronaphthalen-2(1H)-one 
• 39487-54-2 1-((dimethylamino)(phenyl)methyl)naphthalen-2-ol 
• 481-82-3 1-(α-aminobenzyl)-2-naphthol 

Downstream Products

• 40473-53-8 2-Hydroxy-1-(α-hydroxybenzyl)naphthalene 
• 55075-33-7 1-Ethoxy-1-phenyl-1-(2-hydroxy-naphthyl)-methan 
• 35173-74-1 3,3'-bis-indolyl(phenyl)methane 
• 6333-07-9 1-benzoyl-2-naphthol 
• 500352-92-1 (S)-(+)-1-(α-piperidylbenzyl)-2-naphthol 
• 500352-92-1 (R)-(-)-1-(α-piperidylbenzyl)-2-naphthol 
• 36441-31-3 1-benzyl-2-naphthol 

Relevant articles and documents

Facile synthesis of aminoalkyl naphthols and single crystal X-ray, computational studies on 1-[morpholino(thiophen-2-yl)methyl]naphthalen-2-ol

An efficient, eco-friendly protocol is developed for the synthesis of 1- (α-aminoalkyl)-2-naphthol derivatives via one-pot three-component reaction of 2-naphthol, aromatic aldehydes and piperidine or morpholine in the presence of Amberlite IRA-400 Cl resi

Synthesis of 1-aminoalkyl-2-naphthols derivatives using an engineered copper-based nanomagnetic catalyst (Fe3O4@CQD@Si (OEt)(CH2)3NH@CC@N3@phenylacetylene@Cu)

In the present study, a molecular level engineered-based method was used to synthesis a copper-based nanomagnetic catalyst (Fe3O4@CQD@Si (OEt)(CH2)3NH@CC@N3@phenylacetylene@Cu). The as-synthesized cat

Design and identification of nano-Mg-[4-methoxy phenyl-salicylaldimine–methyl-pyranopyrzole] Cl2 and its catalytic application on the preparation of 1-(α-aminoalkyl)-2-naphthols

Nano-Mg- [4-methoxy phenylsalicylaldiminemethylpyranopyrazole]Cl2 (nano-[Mg-4MSMP]Cl2) as a nano-Schiff base complex was prepared and fully characterized using some various techniques including fourier transform infrared spectroscopy