62858-22-4

Basic information

• Product Name: 1(2H)-Pyridinecarboxamide, 3,6-dihydro-N-phenyl-
• CAS NO: 62858-22-4
• Molecular Formula: C12H14N2O
• Molecular Weight: 202.256
• Mol File: 62858-22-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1(2H)-Pyridinecarboxamide, 3,6-dihydro-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1(2H)-Pyridinecarboxamide, 3,6-dihydro-N-phenyl-(62858-22-4)
• EPA Substance Registry System: 1(2H)-Pyridinecarboxamide, 3,6-dihydro-N-phenyl-(62858-22-4)

Safety Data

• Hazardous Substances Data: 62858-22-4(Hazardous Substances Data)

Upstream product

• 694-05-3 1,2,3,6-tetrahydropyridine 
• 103-71-9 phenyl isocyanate 
• 40240-41-3 1-chlorocarbonyl-3,6-dihydro-1(2H)-pyridine 
• 62-53-3 aniline 

Relevant articles and documents

Iodine(V) reagents in organic synthesis. Part 3. New routes to heterocyclic compounds via o-iodoxybenzoic acid-mediated cyclizations: Generality, scope, and mechanism

The discovery and development of the o-iodoxybenzoic acid (IBX) reaction with certain unsaturated N-aryl amides (anilides) to form heterocycles are described. The application of the method to the synthesis of δ-lactams, cyclic urethanes, hydroxy amines, and amino sugars among other important building blocks and intermediates is detailed. In addition to the generality and scope of this cyclization reaction, this article describes a number of mechanistic investigations suggesting a single electron transfer from the anilide functionality to IBX and implicating a radical-based mechanism for the reaction.