629-72-1Relevant articles and documents
Chemoenzymatic synthesis of (S)-eicos-(4E)-en-1-yn-3-ol, the cytotoxic principle of the marine sponge, Cribrochalina vasculum
Sharma, Anubha,Chattopadhyay, Subrata
, p. 2635 - 2639 (1998)
An efficient enantioselective synthesis of the title compound I was developed from the versatile chiron 1-tert-butyldimethylsilylpenta-1,4-diyn- 3-ol 2. The chiron, in turn, was prepared via a combination of lipase catalyzed acylation-alcoholysis protocol. Protection of its hydroxy group, alkylation with a suitable bromide and subsequent functionalization gave (S)- I with high enantiomeric purity.
Photolytic generation of carbon radicals from Barton esters: Recent developments
Barton,Jaszberenyi,Tang
, p. 3381 - 3384 (2007/10/02)
O-Acyl derivatives of N-hydroxy-2-thiopyridone can be photolysed with suitable commercial visible-light lamps to give reactions with very short half-lives (down to 20 s) at 0° C or room temperature.
Quantum Yields in the Photochemically Induced Radical Chemistry of Acyl Derivatives of Thiohydroxamic Acids
Barton, Derek H. R.,Blundell, Paul,Jaszberenyi, Joseph Cs.
, p. 6937 - 6942 (2007/10/02)
Acyl derivatives of N-hydroxyquinazoline-4-thiones are a novel source of disciplined carbon radicals.Quantum yield determination reveals that photolysis of these compounds initiates radical chains, resulting in quantum yields up to φ = 60.Comparative studies with acyl derivatives of N-hydroxy-2-thiopyridone show that the quinazoline derivatives are more light-sensitive than the thiopyridone compounds.The carbon radicals thus formed from the former can be trapped selectively, without the formation of rearranged products (i.e. without the competition of the radicophilic thiocarbonyl group of the starting material with the radical trap).
