6291-85-6Relevant articles and documents
Preparation method of 3-ethoxypropylamine
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Paragraph 0016; 0020-0025, (2019/03/08)
The invention discloses a preparation method of 3-ethoxypropylamine. The preparation method comprises the following steps: 1) adding a catalyst A and ethanol into a reactor; 2) controlling the temperature of the reactor and dripping acrylonitrile; 3) preparing 3-ethoxy propionitrile with the content of more than 97%; 4) hydrogenating the prepared 3-ethoxy propionitrile in the presence of a catalyst B, hydrogen and an inhibitor; and 5) after the hydrogenation is qualified, carrying out vacuum vacuum distillation to obtain a finished product with a content greater than 99.5%. The preparation method has high selectivity, and excessive ethanol and the catalysts A and B in the process can be recycled, thus further reducing the production cost and reducing the discharge amount of waste liquid.
2-aminopyridine derivatives and combinatorial libraries thereof
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, (2008/06/13)
The present invention relates to novel 2-aminopyridine derivative compounds of the following formula: wherein R1to R5have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminopyridine derivative compounds.
Aldose epimerization by Ni(II): effect of ether-containig alkylenediamine ligands
Osanai, Shuichi,Inaba, Kiyoshi,Yoshikawa, Sadao
, p. 289 - 295 (2007/10/02)
Several N-substituted ethylenediamine (en) Ni(II) derivatives containing ether linkages were prepared in order to study the effect of ligand structure on C-2 epimerization of aldohexoses.The reagent consisted of a Ni(II)-alkyenediamine derivative in methanol.The presence of ether linkages in the ligand increased the solubilty of the complexes, and resulted in an increase in the rate of epimerization.Epimerization occured rapidly under mild conditions, and the same equilibrium point was reached regardless of whether the reaction was started from glucose or mannose.Among the ligands studied, N,N'-dialkylethylenediamine was the most effective in C-2 epimerization.