6312-54-5

Basic information

• Product Name: DIMETHYL GLUTAMIC ACID
• Synonyms: DIMETHYL GLUTAMIC ACID
• CAS NO: 6312-54-5
• Molecular Formula: C₇H₁₃NO₄
• Molecular Weight: 175.18242
• Mol File: 6312-54-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 312.7°C at 760 mmHg
• Flash Point: 142.9°C
• Appearance: /
• Density: 1.242g/cm³
• Vapor Pressure: 0.000114mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: DIMETHYL GLUTAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL GLUTAMIC ACID(6312-54-5)
• EPA Substance Registry System: DIMETHYL GLUTAMIC ACID(6312-54-5)

Safety Data

• Hazardous Substances Data: 6312-54-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H13NO4/c1-8(2)5(7(11)12)3-4-6(9)10/h5H,3-4H2,1-2H3,(H,9,10)(H,11,12)

Upstream product

• 50-00-0 formaldehyd 
• 56-86-0 L-glutamic acid 

Downstream Products

• 110-94-1 1,5-pentanedioic acid 
• 2889-31-8 2-hydroxyglutaric acid 
• 72442-37-6 1-methyl-5-oxopyrrolidine-2-carboxylic acid 
• 3885-29-8 (+/-)-tetrahydro-5-oxo-2-furancarboxylic acid methyl ester 
• 1119-40-0 Dimethyl glutarate 
• 178888-44-3 1,5-dimethyl 2-methoxypentanedioate 

Relevant articles and documents

Triple C-H activation of 1,5-bis(di-tert-butylphosphino)-2-(S)-dimethylaminopentane on ruthenium gives a chiral carbene complex

This communication reports the preparation of a novel trans-chelating diphosphine, 1,5-bis(di-tert-butylphosphino)-2-(S)-dimethylaminopentane, that undergoes triple C-H activation in reaction with [RuCl2(p-cymene)]2 to give a chiral square-pyramidal 16-electron carbene complex of ruthenium.

Characterization of N,N-dimethyl amino acids by electrospray ionization-tandem mass spectrometry

Methylation is an essential metabolic process for a number of critical reactions in the body. Methyl groups are involved in the healthy function of the body life processes, by conducting methylation process involving specific enzymes. In these processes, various amino acids are methylated, and the occurrence of methylated amino acids in nature is diverse. Nowadays, mass-spectrometric-based identification of small molecules as biomarkers for diseases is a growing research. Although all dimethyl amino acids are metabolically important molecules, mass spectral data are available only for a few of them in the literature. In this study, we report synthesis and characterization of all dimethyl amino acids, by electrospray ionization-tandem mass spectrometry (MS/MS) experiments on protonated molecules. The MS/MS spectra of all the studied dimethyl amino acids showed preliminary loss of H2O+CO to form corresponding immonium ions. The other product ions in the spectra are highly characteristic of the methyl groups on the nitrogen and side chain of the amino acids. The amino acids, which are isomeric and isobaric with the studied dimethyl amino acids, gave distinctive MS/MS spectra. The study also included MS/MS analysis of immonium ions of dimethyl amino acids that provide information on side chain structure, and it is further tested to determine the N-terminal amino acid of the peptides.