6338-52-9

Basic information

• Product Name: 2-butoxyethylamine
• Synonyms: 2-butoxyethylamine;2-Butoxyethanamine;3-Oxaheptane-1-amine;(2-butoxyethyl)amine hydrochloride;Einecs 228-728-6;2-butoxyethanamine hydrochloride
• CAS NO: 6338-52-9
• Molecular Formula: C₆H₁₅NO
• Molecular Weight: 117.1894
• EINECS: 228-728-6
• Mol File: 6338-52-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 158.3°C at 760 mmHg
• Flash Point: 43°C
• Appearance: /
• Density: 0.851g/cm³
• Vapor Pressure: 2.64mmHg at 25°C
• Refractive Index: 1.424
• CAS DataBase Reference: 2-butoxyethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-butoxyethylamine(6338-52-9)
• EPA Substance Registry System: 2-butoxyethylamine(6338-52-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 6338-52-9(Hazardous Substances Data)

Usage

General Description

2-butoxyethylamine is a chemical compound with the formula C6H15NO. It is a clear, colorless liquid with a mild ammonia-like odor. This chemical is commonly used as a solvent in the production of pesticides, herbicides, and cleaning products. It is also utilized as an intermediate in the synthesis of various chemicals and pharmaceuticals. 2-butoxyethylamine is considered to be a hazardous substance and exposure to high concentrations can cause irritation to the skin, eyes, and respiratory system. Therefore, proper handling and storage procedures are essential to minimize potential health and safety risks.

InChI:InChI=1/C6H15NO/c1-2-3-5-8-6-4-7/h2-7H2,1H3

Upstream product

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Downstream Products

• 107412-46-4 (2-butoxy-ethyl)-(2,4-dichloro-benzyl)-amine 
• 162688-35-9 2-<<5-<(2-butoxyethyl)amino>pentyl>thio>-4,5-diphenyl-1H-imidazole 
• 162688-34-8 N-(2-butoxyethyl)-5-<(4,5-diphenyl-1H-imidazol-2-yl)thio>pentanamide 
• 65329-76-2 1-(2-butoxyethyl)-4-phenyl-4-imidazolin-2-one 
• 75945-76-5 1-(2-butoxyethyl)-4-phenyl-2-imidazolidone 
• 791-61-7 N-Nitroso-N-<2-butyloxy-ethyl>-p-toluolsulfonamid 

Relevant articles and documents

Direct Access to Primary Amines from Alkenes by Selective Metal-Free Hydroamination

Direct and selective synthesis of primary amines from easily available precursors is attractive yet challenging. Herein, we report the rapid synthesis of primary amines from alkenes via metal-free regioselective hydroamination at room temperature. Ammonium carbonate was used as ammonia surrogate for the first time, allowing for efficient conversion of terminal and internal alkenes into linear, α-branched, and α-tertiary primary amines under mild conditions. This method provides a straightforward and powerful approach to a wide spectrum of advanced, highly functionalized primary amines which are of particular interest in pharmaceutical chemistry and other areas.

Design, Synthesis, and Structure-Activity Relationship Studies for a New Imidazole Series of J774 Macrophage Specific Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitors

Acyl-CoA:cholesterol acyltransferase (ACAT) is the primary enzyme involved in intracellular cholesterol esterification.Arterial wall infiltration by macrophages and subsequent uncontrolled esterification of cholesterol leading to foam cell formation is believed to be an important process which leads to the development of fatty streaks.Inhibitors of the ACAT enzyme may retard this atherogenic process.We have recently discovered a series of imidazoles which are potent in vitro ACAT inhibitors in the J774 macrophage cell culture assay.This paper will describe the design, synthesis, and structure-activity relationship for this very potent series of compounds.