6340-79-0

Basic information

• Product Name: 3-(4-BROMOBENZOYL)PROPIONIC ACID
• Synonyms: TIMTEC-BB SBB000956;3-(P-BROMOBENZOYL)PROPIONIC ACID;4-(4-BROMOPHENYL)-4-OXOBUTANOIC ACID;4-(4-BROMOPHENYL)-4-OXOBUTYRIC ACID;3-(4-BROMOBENZOYL)PROPIONIC ACID;BETA-(P-BROMOBENZOYL)PROPIONIC ACID;Benzenebutanoic acid, 4-bromo-gamma-oxo-;3-(4-BROMOBENZOYL)PROPIONIC ACID, 98+%
• CAS NO: 6340-79-0
• Molecular Formula: C₁₀H₉BrO₃
• Molecular Weight: 257.08
• EINECS: 228-732-8
• Product Categories: Aromatic Propionic Acids;C10;Carbonyl Compounds;Carboxylic Acids
• Mol File: 6340-79-0.mol
• Article Data: 64

Chemical Properties

• Melting Point: 148-152 °C(lit.)
• Boiling Point: 428 °C at 760 mmHg
• Flash Point: 212.6 °C
• Appearance: White to light beige/Shiny Crystalline Flakes or Powder
• Density: 1.5943 (rough estimate)
• Vapor Pressure: 4.37E-08mmHg at 25°C
• Refractive Index: 1.4620 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.44±0.17(Predicted)
• BRN: 2104410
• CAS DataBase Reference: 3-(4-BROMOBENZOYL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-BROMOBENZOYL)PROPIONIC ACID(6340-79-0)
• EPA Substance Registry System: 3-(4-BROMOBENZOYL)PROPIONIC ACID(6340-79-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 6340-79-0(Hazardous Substances Data)

Usage

Chemical Properties

white to light beige shiny crystalline flakes

InChI:InChI=1/C10H9BrO3/c11-8-3-1-7(2-4-8)9(12)5-6-10(13)14/h1-4H,5-6H2,(H,13,14)/p-1

Upstream product

• 108-30-5 succinic acid anhydride 
• 108-86-1 bromobenzene 
• 60-29-7 diethyl ether 
• 861777-42-6 4-(4-bromo-benzoyl)-5-phenyl-dihydro-furan-2-one 
• 124-41-4 sodium methylate 
• 85060-86-2 2,2-dimethyl-5-(p-bromophenacyl)-1,3-dioxane-4,6-dione 
• 856099-40-6 5-(4-bromo-phenyl)-5-hydroxy-1-methyl-pyrrolidin-2-one 
• 7664-93-9 sulfuric acid 
• 20005-42-9 5-(4-bromophenyl)-2-furancarboxyaldehyde 
• 81008-11-9 C₁₀H₉BrO₄ 
• 99-90-1 para-bromoacetophenone 
• 2403-27-2 1-(4-bromophenyl)-3-phenyl-2-propen-1-one 
• 90766-44-2 (E)-4-oxo-4-(4-bromophenyl)-2-butenamide 
• 7477-66-9 4-oxo-4-(4-bromo-phenyl)-trans-crotonic acid-chloride 

Downstream Products

• 60112-48-3 5-(p-bromophenyl)-β,γ-butenolide 
• 35656-89-4 4-(4-bromophenyl)butanoic acid 
• 1821-12-1 4-Phenylbutyric acid 
• 30913-86-1 4-(4-bromo-phenyl)-4-oxo-butyric acid methyl ester 
• 124-38-9 carbon dioxide 
• 586-76-5 4-Bromobenzoic acid 
• 35158-41-9 3-bromo-4-(4-bromophenyl)-4-oxobutanoic acid 
• 97728-47-7 dimethyl 2-(4-bromophenyl)succinate 
• 223103-44-4 5-(4-Bromo-phenyl)-3-[1-(4-bromo-phenyl)-meth-(Z)-ylidene]-3H-furan-2-one 
• 223103-42-2 5-(4-bromo-phenyl)-3-(3-methyl-benzylidene)-3H-furan-2-one 
• 339079-97-9 3-(4-Methylphenyl)-5-[2-(4-bromophenyl)-2-oxoethyl]-4-oxo-2-thioxo-1,3-thiazolidine 
• 30913-87-2 4-(4-bromophenyl)-4-oxobutanoic acid ethyl ester 
• 375826-29-2 decyl 4-(4-bromophenyl)-4-oxobutanoate 
• 375826-30-5 dodecyl 4-(4-bromophenyl)-4-oxobutanoate 

Relevant articles and documents

Pd Nanoparticles Embedded Into MOF-808: Synthesis, Structural Characteristics, and Catalyst Properties for the Suzuki–Miyaura Coupling Reaction

Abstract: A heterogeneous single-site catalyst Pd@MOF-808 was successfully synthesized by water-based, green synthesis procedure. The catalytic experiments exhibited the Pd@MOF-808 promoted efficiently the Suzuki–Miyaura coupling reaction without the assistance of organic phosphine ligands at atmospheric pressure conditions. The catalyst also could be applied in the gram-scale synthesis of industrially anti-inflanmatory analgestic Fenbufen. Graphic Abstract: [Figure not available: see fulltext.]

Tetrakis(4-formylphenyl) ferrocene and preparation method and application thereof

The invention relates to the technical field of material synthesis, in particular to tetrakis(4-formylphenyl) ferrocene as well as a preparation method and application thereof. The preparation method comprises the following steps: in a nitrogen atmosphere, dropwise adding n-butyllithium into a tetrahydrofuran solution in which tetrakis(4-X-phenyl) ferrocene is dissolved, controlling the temperature and stirring, with the X being Br or I; then dropwise adding N,N-dimethylformamide, and after the N,N-dimethylformamide is completely added, controlling the temperature and stirring; transferring the reaction liquid into diluted hydrochloric acid, and stirring to separate out a solid; and filtering the separated solid, washing with methanol, re-dissolving the washed solid with ethyl acetate, and carrying out reduced pressure rotary evaporation on the obtained solution. The prepared tetrakis(4-formylphenyl) ferrocene can be condensed with aromatic amine to form an imine bond, so that a ferrocene structure is combined with a COFs structure to form a novel MCOFs material, the novel MCOFs material has excellent physical and chemical properties of ferrocene, a large number of metal active sites can be provided, and the structure is stable.

Synthesis, anti-convulsant activity and molecular docking study of novel thiazole pyridazinone hybrid analogues

Pyridazinone analogues have been known to be potential candidates for anticonvulsant agents. We have identified several pyridazinone-based anticonvulsant agents. As a continuation to our previous research, a series of hybrid pyridazinone-thiazole connected through amide linkage were designed and synthesized. Among these, compound SP-5F demonstrated significant anticonvulsant activity with median effective dose of 24.38 mg/kg (MES) and 88.23 mg/kg (scPTz). Results of GABA estimation showed a marked increase in the GABA level when compared with control. Molecular docking studies at the active site of GABA receptor, further confirmed the GABA modulatory effects of SP-5F.