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TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE is a complex spiro-structure chemical compound characterized by a molecular formula of C21H28ClN3O2. It features an indoline ring fused with a piperidine ring, with a tert-butyl group attached at the 5-position of the indoline ring and a chloro group present within the molecule. The unique structural features of this compound suggest potential pharmaceutical applications, making it a candidate for the development of new drugs and therapeutic agents.

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  • tert-butyl 5-chlorospiro[1,2-dihydroindole-3,4'-piperidine]-1'-carboxylate

    Cas No: 637362-21-1

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  • 637362-21-1 Structure
  • Basic information

    1. Product Name: TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE
    2. Synonyms: TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE;tert-butyl 5-chlorospiro[indoline-3,4'-piperidine]-1'-carboxylat;tert-butyl 5-chlorospiro[1,2-dihydroindole-3,4'-piperidine]-1'-carboxylate;tert-Butyl 5-chloro-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-carboxylate
    3. CAS NO:637362-21-1
    4. Molecular Formula: C17H23ClN2O2
    5. Molecular Weight: 322.834
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 637362-21-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 452.7±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.23±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 4.59±0.20(Predicted)
    10. CAS DataBase Reference: TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE(637362-21-1)
    12. EPA Substance Registry System: TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE(637362-21-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 637362-21-1(Hazardous Substances Data)

637362-21-1 Usage

Uses

Used in Pharmaceutical Industry:
TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE is used as a key intermediate in the synthesis of various drugs due to its unique spiro-structure and functional groups. Its presence in the molecular framework can influence the biological activity and pharmacological properties of the resulting compounds.
Used in Drug Development:
TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE is used as a potential therapeutic agent for the treatment of various diseases and conditions. Its structural features may contribute to its ability to interact with biological targets, such as receptors, enzymes, or other proteins, thereby modulating their activity and potentially leading to therapeutic effects.
Used in Medicinal Chemistry Research:
TERT-BUTYL 5-CHLOROSPIRO[INDOLINE-3,4'-PIPERIDINE]-1'-CARBOXYLATE serves as a valuable compound in medicinal chemistry research, where it can be used to explore structure-activity relationships and optimize the design of new drug candidates. Its unique spiro-structure and functional groups provide a foundation for further chemical modifications and the development of more potent and selective agents.

Check Digit Verification of cas no

The CAS Registry Mumber 637362-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,7,3,6 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 637362-21:
(8*6)+(7*3)+(6*7)+(5*3)+(4*6)+(3*2)+(2*2)+(1*1)=161
161 % 10 = 1
So 637362-21-1 is a valid CAS Registry Number.

637362-21-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 5-chlorospiro[1,2-dihydroindole-3,4'-piperidine]-1'-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:637362-21-1 SDS

637362-21-1Relevant articles and documents

S PIROINDOLINE COMPOUNDS FOR USE AS ANTHELMINTHI CS

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, (2011/09/14)

This invention relates to spiroindoline compounds for the treatment of helminth infections and the treatment of parasitosis, such as caused by helminth infections. This invention also relates to uses of the compounds to make medicaments and treatments com

PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS

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Page/Page column 74, (2009/09/04)

The present invention provides compounds of Formula (I) including tautomers, resolved enantiomers, resolved diastereomers, solvates, metabolites, salts and pharmaceutically acceptable prodrugs thereof. Also provided are methods of using the compounds of this invention as Akt protein kinase inhibitors and for the treatment of Akt-mediated diseases, for example, hyperproliferative diseases such as cancer.

SPIROINDOLINEPIPERIDINE DERIVATIVES

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Page 101, (2008/06/13)

Insecticidal, acaricidal, nematicidal or molluscicidal compounds of formula (I) wherein Y is a single bond, C=O, C=S or C=(O)q where q is 0, 1 or 2; and R1, R2, R3, R4, R8, R9 an

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