638-21-1

Basic information

• Product Name: Phenyl phosphine
• Synonyms: Phenylphosphine,99%(10wt%inhexane);Phenylphosphine,99%(Sure/Sealbottle);PHPH2;PHENYLPHOSPHINE (10% WT. IN HEXANE);Phenylphosphine ca. 10% weight in hexanes;Phenylphosphine, 99% (Sure/Seal TM bottle);Phenylphosphine (Sure/Seal bottle);AURORA KA-1101
• CAS NO: 638-21-1
• Molecular Formula: C₆H₇P
• Molecular Weight: 110.09
• EINECS: 211-325-4
• Product Categories: Catalysis and Inorganic Chemistry;Phosphine Ligands;Phosphorus Compounds;organophosphorus ligand;organophosphine ligand
• Mol File: 638-21-1.mol
• Article Data: 53

Chemical Properties

• Melting Point: 148-151 °C
• Boiling Point: 160°C
• Flash Point: -20°F
• Appearance: colorless/liquid
• Density: 1.001
• Vapor Density: 3.79 (vs air)
• Vapor Pressure: 3.09mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: ?20°C
• Water Solubility: Insoluble in water.
• Sensitive: Air & Moisture Sensitive
• BRN: 741946
• CAS DataBase Reference: Phenyl phosphine(CAS DataBase Reference)
• NIST Chemistry Reference: Phenyl phosphine(638-21-1)
• EPA Substance Registry System: Phenyl phosphine(638-21-1)

Safety Data

• Hazard Codes: F;T;N,N,T,F,Xn
• Statements: 11-17-23/24/25-36/37/38-48/20-51/53-62-65-67-38-20/21/22
• Safety Statements: 16-26-36/37/39-45-62-61-36/37
• RIDADR: 2924
• WGK Germany: 3
• RTECS: SZ2100000
• HazardClass: 4.2
• PackingGroup: I
• Hazardous Substances Data: 638-21-1(Hazardous Substances Data)

Usage

Chemical Properties

Phenylphosphine is a clear, colorless liquid. Foul odor.

Uses

Different sources of media describe the Uses of 638-21-1 differently. You can refer to the following data:
1. suzuki reaction
2. Exposure to phenylphosphine may occur when phenylphosphinates (used as catalysts and antioxidants) are heated above 200°C, yielding phenylphosphonic acid derivatives and phenylphosphine.
3. It is mainly used as a precursor to other organophosphorus compounds. It can function as a?ligand?in coordination chemistry. Phenylphosphine also have uses in polymer synthesis.

General Description

Clear colorless liquid.

Air & Water Reactions

Pyrophoric in air. Insoluble in water. Slowly generates flammable or noxious gases in contact with water.

Reactivity Profile

Phenyl phosphine is a reducing agent. They slowly generate flammable or noxious gases in contact with water. Phosphides react quickly upon contact with moisture or acids to give the very toxic gas phosphine; phosphides also can react vigorously with oxidizing materials. In general, materials in this group are incompatible with oxidizers such as atmospheric oxygen. They are violently incompatible with acids, particularly oxidizing acids.

Health Hazard

Phenylphosphine is a respiratory and skin irritant; multiple exposures in rodents causes hematologic changes and testicular degeneration in males.

Fire Hazard

Flash point data are not available for Phenyl phosphine, but Phenyl phosphine is probably combustible.

Safety Profile

Poison by inhalation. Igmtes spontaneously in air. When heated to decomposition it emits toxic fumes of POx. See also PHOSPHINE.

Potential Exposure

Polyphosphinate is used as an intermediate or a chemical reagent. Polyphosphinate compounds are used as catalysts and antioxidants disproportionate, when heated to give phosphonic acid derivatives plus PF.

Shipping

UN2845 Pyrophoric liquids, organic, n.o.s Hazard Class: 4.2, Labels: 4.2-Spontaneously combustible material. Technical Name Required. Note: this chemical is also a strong reducing agent.

Incompatibilities

A strong reducing agent. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Water reactive; spontaneously combustible in high concentrations in moist air. Potential exposure to gaseous phenylphosphine and phosphorus oxides when heated above 200C. Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrideds and active metals. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

InChI:InChI=1/C6H7P/c7-6-4-2-1-3-5-6/h1-5H,7H2

Upstream product

• 64-17-5 ethanol 
• 1486-37-9 phenyl-dithiophosphonous acid diethyl ester 
• 57680-64-5 8-Phenyl-tetrahydro-8λ⁵-[1,3,2]oxazaphospholo[2,3-b][1,3,2]oxazaphosphole 
• 108-86-1 bromobenzene 
• 82312-25-2 (C₂H₅)2GeP(C₆H₅) 
• 30711-42-3 thiophosphoroso-benzene 
• 7732-18-5 water 
• 1073-47-8 phenyldibromophosphine 
• 1754-49-0 diethyl phenylphosphonate 
• 591-50-4 iodobenzene 
• 205433-91-6 [α-(phenylphosphanyl)benzylidene]triphenylphosphorane 
• 3376-52-1 pentaphenylcyclopentaphosphane 
• 28240-64-4 bis(diphenylphosphino)methane 
• 67-56-1 methanol 

Downstream Products

• 2176-06-9 diphenyldiphosphene 
• 19172-39-5 Propionylphenylphosphin 
• 1087-60-1 <1-Hydroxy-cyclopentyl>-cyclopentyl-phenyl-phosphinoxid 
• 130748-11-7 1-[(2-Hydroxy-3,3-dimethyl-butyl)-phenyl-phosphanyl]-3,3-dimethyl-butan-2-ol 
• 18899-56-4 P,P'-diphenyl-1,4-diphospha-cyclohexane 
• 22846-16-8 ethylene phenyl phosphite 
• 40012-64-4 1,2,3-triphenyl-1,2,3-triphospholane 
• 73373-21-4 bis(3-chloropropyl)phenylphosphine 
• 54722-12-2 isopropyl(phenyl)phosphine 
• 22366-73-0 (+/-)-benzylphenylphosphane 
• 4722-60-5 2,4,5,6-tetraphenyl-[1,3,5]dioxaphosphinane 
• 1005-21-6 trimethylphenylphosphonium iodide 
• 1499-40-7 trimethyl-phenyl-phosphonium; picrate 
• 30711-42-3 thiophosphoroso-benzene 

Relevant articles and documents

PHOSPHORANES BICYCLIQUES A LIAISON P-H : BASES DE LEWIS POTENTIELLES

By reaction of Borane Dimethyl Sulfide on the bicyclophosphorane 1 the adduct 2 is obtained with 56 percent yield; by-products 3 and 4 are characterized.

-

-

Process for preparation of phosphorane and phosphonyl compounds

The invention relates to the field of new materials of fine chemicals, in particular to a new safe, convenient, mild, efficient, environment-friendly and economical preparation process technology of phosphorane and phosphonyl compounds.

Photocatalytic Arylation of P4 and PH3: Reaction Development Through Mechanistic Insight

Detailed 31P{1H} NMR spectroscopic investigations provide deeper insight into the complex, multi-step mechanisms involved in the recently reported photocatalytic arylation of white phosphorus (P4). Specifically, these studies have identified a number of previously unrecognized side products, which arise from an unexpected non-innocent behavior of the commonly employed terminal reductant Et3N. The different rate of formation of these products explains discrepancies in the performance of the two most effective catalysts, [Ir(dtbbpy)(ppy)2][PF6] (dtbbpy=4,4′-di-tert-butyl-2,2′-bipyridine) and 3DPAFIPN. Inspired by the observation of PH3 as a minor intermediate, we have developed the first catalytic procedure for the arylation of this key industrial compound. Similar to P4 arylation, this method affords valuable triarylphosphines or tetraarylphosphonium salts depending on the steric profile of the aryl substituents.

Tailoring Phospholes for Imprint of Fluorescent 3D Structures

PMMA based polymer blends have been infused with luminescent phospholes and have been structured via nanoimprint. While symmetrically substituted phospholes are prone to crystallization and phase separation, structural modification of the phosphole backbone in the α- and β-positions has been explored, which prevents these issues; a structural explanation for this is suggested. Best phase integrity has been obtained for β-silyl-substituted phospholes, which were implemented in thin films and beads. The emission wavelengths of the phospholes are shifted bathochromically in the polymer matrix as compared to the neat compounds featuring emission bands near 500 nm. This enables tracking of the fluorescent beads using standard fluorescence microscopy.