638191-38-5

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 4-[[1-(2-bromo-3-phenyl-2-propenyl)-4-piperidinyl]amino]-6-chloro-, mono(trifluoroacetate)
• CAS NO: 638191-38-5
• Molecular Formula: C23H22BrClN2O2.C2HF3O2
• Molecular Weight: 587.821
• Mol File: 638191-38-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 4-[[1-(2-bromo-3-phenyl-2-propenyl)-4-piperidinyl]amino]-6-chloro-, mono(trifluoroacetate)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 4-[[1-(2-bromo-3-phenyl-2-propenyl)-4-piperidinyl]amino]-6-chloro-, mono(trifluoroacetate)(638191-38-5)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 4-[[1-(2-bromo-3-phenyl-2-propenyl)-4-piperidinyl]amino]-6-chloro-, mono(trifluoroacetate)(638191-38-5)

Safety Data

• Hazardous Substances Data: 638191-38-5(Hazardous Substances Data)

Upstream product

• 638191-32-9 6-chloro-4-(piperidin-4-ylamino)chromen-2-one 
• 5443-49-2 α-bromocinnamaldehyde 

Relevant articles and documents

ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR

This invention provides compounds that are antagonists of melanin concentrating hormone receptor-1 (MCH-R1). The compounds are represented by formula (I): where m is zero or one, n is zero to two, Y is oxygen or -N (R9)-, R1, R2, R3, R4, R5, R9, and Ring A are defined in the specification. Coumarin and quinolone compounds where R1 and R2 together form a fused benzo ring are preferred. The invention also provides compounds of formula (VI) where the coumarin moiety is replaced by a quinazolinone ring. The compounds are useful for treating MCH-R1-related disorders, particularly overweight conditions including obesity.