64099-82-7

Basic information

• Product Name: TRIBUTYLPROPYNYLSTANNANE
• Synonyms: PROPYNYLTRI-N-BUTYLTIN;Tributyl-1-propynylstannane;TRIBUTYLPROPYNYLSTANNANE;(1-PROPYNYL)TRIBUTYLSTANNANE;1-PROPYNYLTRI-N-BUTYLTIN;tech.80%;Tributyl-1-propynylstannane, tech., 80%;Tributyl-1-propynylstannane, 80%, tech.
• CAS NO: 64099-82-7
• Molecular Formula: C₁₅H₃₀Sn
• Molecular Weight: 329.11
• Product Categories: Organometallic Reagents;Organotin;Organotins;Stannanes
• Mol File: 64099-82-7.mol

Chemical Properties

• Boiling Point: 277 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.082 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000768mmHg at 25°C
• Refractive Index: n20/D 1.483(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive: Air Sensitive
• CAS DataBase Reference: TRIBUTYLPROPYNYLSTANNANE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIBUTYLPROPYNYLSTANNANE(64099-82-7)
• EPA Substance Registry System: TRIBUTYLPROPYNYLSTANNANE(64099-82-7)

Safety Data

• Hazard Codes: T,N
• Statements: 21-25-36/38-48/23/25-50/53
• Safety Statements: 35-36/37/39-45-60-61
• RIDADR: UN 2788 6.1/PG 3
• WGK Germany: 3
• TSCA: No
• HazardClass: 6.1
• PackingGroup: II
• Hazardous Substances Data: 64099-82-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
TRIBUTYLPROPYNYLSTANNANE is used as a starting material for the synthesis of phenyl-substituted pyrimidine-dione by reacting with ethyl isocyanate via cycloaddition and Stille coupling reactions. TRIBUTYLPROPYNYLSTANNANE has potential applications in the development of new pharmaceutical agents.
Used in Positron Emission Tomography (PET) Imaging:
TRIBUTYLPROPYNYLSTANNANE is used in the synthesis of 18F labeled triazolo quinoline derivative, a PET ligand used in the in vivo imaging of metabotropic glutamate receptor type 1 (mGluR1). This application aids in the visualization and study of mGluR1-related neurological disorders.
Used in the Synthesis of mGluR1 Antagonists:
TRIBUTYLPROPYNYLSTANNANE is used as a key synthetic intermediate in the synthesis of 4-(1-aryltriazol-4-yl)-tetrahydropyridines, which are potent mGluR1 antagonists. These antagonists have potential therapeutic applications in the treatment of various neurological and psychiatric disorders, such as anxiety, depression, and schizophrenia.

InChI:InChI=1/3C4H9.C3H3.Sn/c3*1-3-4-2;1-3-2;/h3*1,3-4H2,2H3;1H3;/rC15H30Sn/c1-5-9-13-16(12-8-4,14-10-6-2)15-11-7-3/h5-7,9-11,13-15H2,1-4H3

Downstream Products

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