64517-78-8

Basic information

• Product Name: 4H-[1]Benzopyrano[3,4-d]isoxazol-4-one, 3-phenyl-
• CAS NO: 64517-78-8
• Molecular Formula: C16H9NO3
• Molecular Weight: 263.252
• Mol File: 64517-78-8.mol

Chemical Properties

• CAS DataBase Reference: 4H-[1]Benzopyrano[3,4-d]isoxazol-4-one, 3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-[1]Benzopyrano[3,4-d]isoxazol-4-one, 3-phenyl-(64517-78-8)
• EPA Substance Registry System: 4H-[1]Benzopyrano[3,4-d]isoxazol-4-one, 3-phenyl-(64517-78-8)

Safety Data

• Hazardous Substances Data: 64517-78-8(Hazardous Substances Data)

Upstream product

• 19492-11-6 3-benzoyl-4-hydroxy-2H-chromen-2-one 
• 129207-82-5 ethyl trans-3-phenyl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylate 
• 77037-46-8 2-phenyl-4-oxo-4H-chromene-3-carboxylic acid ethyl ester 
• 3943-94-0 (E)-ethyl 2-hydroxycinnamate 
• 698-16-8 benzohydroximoyl chloride 

Downstream Products

• 79280-17-4 [3-Phenyl-chromeno[3,4-d]isoxazol-(4E)-ylidene]-hydrazine 

Relevant articles and documents

A Convenient Synthesis of 3-Aryl-4H-benzopyranoisoxazol-4-ones

Regioselective 1,3-dipolar cycloaddition of nitrile oxides 5a-c to ethyl o-hydroxycinnamate (3) gave the corresponding ethyl trans-3-aryl-4,5-dihydro-5-(2-hydroxyphenyl)-4-isoxazolecarboxylates 6a-c.Their structure was confirmed by reductive cleavage to 1 and compounds 9a-c.Compounds 6a-c afforded upon heating in the presence of pyridine the 3-aryl-4H-benzopyranoisoxazol-4-ones 11a-c.Compound 10c was also isolated from 6c and transformed thermally into 11c.

Synthesis of Benzopyranoisoxazol-4-ones from 2-Substituted Chromone-3-carboxylic Esters. A Reinvestigation of the Reaction of 3-Acetyl-4-hydroxycoumarins with Hydroxylamine. Synthesis of 4-(2-Hydroxybenzoyl)isoxazol-5-ones

A convenient method for the synthesis of ethyl 2-substituted chromone-3-carboxylates by the condensation of o-acetoxyaroyl chlorides with β-keto esters is described.These chromones are converted into the corresponding 4H-benzopyranoisoxazol-4-on