6453-95-8Relevant articles and documents
Ring-size-selective construction of fluorine-containing carbocycles via intramolecular iodoarylation of 1,1-difluoro-1-alkenes
Fujita, Takeshi,Kinoshita, Ryo,Takanohashi, Tsuyoshi,Suzuki, Naoto,Ichikawa, Junji
, p. 2682 - 2689 (2017)
1,1-Difluoro-1-alkenes bearing a biaryl-2-yl group effectively underwent site-selective intramolecular iodoarylation by the appropriate cationic iodine species. Iodoarylation of 2-(2-aryl-3,3-difluoroallyl)biaryls proceeded via regioselective carbon-carbon bond formation at the carbon atoms in β-position to the fluorine substituents, thereby constructing dibenzo-fused six-membered carbocycles bearing a difluoroiodomethyl group. In contrast, 2-(3,3-difluoroallyl)biaryls underwent a similar cyclization at the α-carbon atoms to afford ring-difluorinated seven-membered carbocycles.
Formal Enone α-Arylation via I(III)-Mediated Aryl Migration/Elimination
Martins, Bruna S.,Kaiser, Daniel,Bauer, Adriano,Tiefenbrunner, Irmgard,Maulide, Nuno
, p. 2094 - 2098 (2021/04/05)
A formal enone α-arylation is described. This metal-free transformation relies on the I(III)-mediated skeletal reorganization of silyl enol ethers and features mild conditions, good yields, and high stereoselectivities for β-substituted enones.
Synthesis of Phenanthrenes through Visible-Light Photoredox Catalyzed Intramolecular Cyclization of α-Bromochalcones
Nagode, Savita B.,Kant, Ruchir,Rastogi, Namrata
supporting information, p. 1533 - 1537 (2018/04/20)
A mild and efficient photocatalytic protocol for the synthesis of the phenanthrene scaffold has been devised. The reaction involves intramolecular cyclization of α-keto vinyl radicals generated from α-bromochalcones under visible light photoredox catalyze
