64576-54-1

Basic information

• Product Name: 3,4-dimethyl-5-(pyridin-2-ylmethylidene)-1,5-dihydro-2H-pyrrol-2-one
• CAS NO: 64576-54-1
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.2365
• Mol File: 64576-54-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 425.9°C at 760 mmHg
• Flash Point: 211.4°C
• Density: 1.167g/cm³
• Vapor Pressure: 1.84E-07mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: 3,4-dimethyl-5-(pyridin-2-ylmethylidene)-1,5-dihydro-2H-pyrrol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethyl-5-(pyridin-2-ylmethylidene)-1,5-dihydro-2H-pyrrol-2-one(64576-54-1)
• EPA Substance Registry System: 3,4-dimethyl-5-(pyridin-2-ylmethylidene)-1,5-dihydro-2H-pyrrol-2-one(64576-54-1)

Safety Data

• Hazardous Substances Data: 64576-54-1(Hazardous Substances Data)

Upstream product

• 64576-55-2 E-3,4-dimethyl-5-(2-pyridylmethylidene)-3-pyrrolin-2-one 
• 1121-60-4 pyridine-2-carbaldehyde 
• 4030-22-2 3,4-dimethyl-3-pyrrolin-2-one 

Relevant articles and documents

SYNTHESIS AND PROPERTIES OF 2,2'-PYRROMETHENE-5(1H)-ONE ANALOGUES: THE FURAN, THIOPHENE, BENZENE, 4-METHOXYBENZENE, 2-PYRIDINE AND 4-PYRIDINE ANALOGUES

Condensation of furfural, thiophene-2-carboxaldehyde, benzaldehyde, 4-methoxy-benzaldehyde, pyridine-2-carboxaldehyde and pyridine-4-carboxaldehyde with 3,4-dimethyl-3-pyrrolin-2-one leads to the Z-2,2'-pyrromethene-5(1H)-one analogues.Following irradiation with light, the E forms have been isolated and characterized.Complete thermal E -> Z isomerisation is observed upon heating in basic methanol.On irradiation in non hydrogen-donating solvents the analogues 3a, 3b and 3e show very little or no photoisomerisation due to the intramolecular hydrogen bond.Condensation of these aldehydes with 1,3,4-trimethyl-3-pyrrolin-2-one gives mixtures of the corresponding Z- and E-2,2'-pyrromethene-5(1H)-one analogues.The Z and E forms both isomerise thermally upon heating in basic methanol to give the same equilibrium state as is observed during the synthesis.Upon irradiation with light, the compounds similarly undergo Z-E isomerisation.