64588-82-5

Basic information

• Product Name: 5-fluorothiazol-2-amine
• Synonyms: 2-Thiazolamine, 5-Fluoro-;5-Fluoro-2-Aminothiazol;5-Fluoro-2-thiazolamine;5-fluorothiazol-2-amine;5-Fluoro-thiazol-2-ylaMine;5-Fluoro-2-thiazolaMine hydrochloride;5-Fluoro-2-thiazolaMine h...;2-Amino-5-fluorothiazole hydrochloride
• CAS NO: 64588-82-5
• Molecular Formula: C₃H₃FN₂S
• Molecular Weight: 118
• Mol File: 64588-82-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 221.838 °C at 760 mmHg
• Flash Point: 87.965 °C
• Appearance: /
• Density: 1.502 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5-fluorothiazol-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluorothiazol-2-amine(64588-82-5)
• EPA Substance Registry System: 5-fluorothiazol-2-amine(64588-82-5)

Safety Data

• RIDADR: UN2811
• Hazardous Substances Data: 64588-82-5(Hazardous Substances Data)

Usage

General Description

5-fluorothiazol-2-amine is a chemical compound with the molecular formula C4H4FN3S. It is a fluorinated thiazole derivative that contains an amine functional group. 5-fluorothiazol-2-amine is used in organic synthesis as a building block for the development of pharmaceutical and agrochemical products. It has potential applications in the field of medicinal chemistry for the synthesis of new drug candidates. Additionally, 5-fluorothiazol-2-amine may also be used as a research tool in the study of chemical reactions and transformations involving thiazole and amine moieties.

Upstream product

• 40283-46-3 2-aminothiazole-5-carboxylic acid 
• 876379-99-6 2-acetamido-5-fluorothiazole 
• 731018-54-5 2-(tert-butoxycarbonyl)amino-5-fluorothiazole 
• 745053-64-9 5-fluoro-1,3-thiazol-2-amine hydrochloride 

Downstream Products

• 1309612-59-6 C₁₂H₉FN₂O₃S 
• 1209458-83-2 2-bromo-5-fluorothiazole 
• 1596340-73-6 N-(5-fluorothiazol-2-yl)-3-(4-methanesulfonylphenoxy)-5-(3-methylpyridin-2-yl)benzamide 
• 1282520-13-1 3-[trans-2-(2-methoxyphenyl)vinyl]-5-(2-methoxy-(1S)-methyl-ethoxy)-N-(5-fluorothiazol-2-yl)-benzamide 
• 1374986-68-1 N-(5-fluorothiazol-2-yl)-3-(4-((4-methoxypiperidin-1-yl)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzamide 
• 1374986-66-9 (S)-3-(4-((3-fluoropyrrolidin-1-yl)sulfonyl)phenoxy)-N-(5-fluorothiazol-2-yl)-5-((3-methylbut-2-en-1-yl)oxy)benzamide 
• 1374986-58-9 3-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenoxy)-N-(5-fluorothiazol-2-yl)-5-((3-methylbut-2-en-1-yl)oxy)benzamide 
• 1374986-56-7 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-N-(5-fluorothiazol-2-yl)-5-((3-methylbut-2-en-1-yl)oxy)benzamide 
• 1374986-54-5 N-(5-fluorothiazol-2-yl)-3-((3-methylbut-2-en-1-yl)oxy)-5-(4-(morpholinosulfonyl)phenoxy)benzamide 
• 1374986-52-3 3-(4-(cyclopropylsulfonyl)phenoxy)-N-(5-fluorothiazol-2-yl)-5-((3-methylbut-2-en-1-yl)oxy)benzamide 
• 1336804-28-4 C₁₁H₆FN₃O₂S 
• 1103523-25-6 (S)-2-(4-chlorophenyl)-N-(5-fluorothiazol-2-yl)-3-methylbutanamide 
• 1208553-15-4 C₁₃H₁₂ClFN₂OS 
• 1208552-92-4 C₁₅H₁₆ClFN₂OS 

Relevant articles and documents

ALPHA-D-GALACTOSIDE INHIBITORS OF GALECTINS

The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human. Furthermore, the present invention concerns a method for treatment of a disorder relating to the binding of a galectin, such as galectin-1 to a ligand in a mammal, such as a human.

Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication

We report the syntheses and activities of a wide range of thiazolides [viz., 2-hydroxyaroyl-N-(thiazol-2-yl)amides] against hepatitis B virus replication, with QSAR analysis of our results. The prototypical thiazolide, nitazoxanide [2-hydroxybenzoyl-N-(5-

GLUCOKINASE ACTIVATORS

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