6482-34-4

Basic information

• Product Name: Diisopropyl carbonate
• Synonyms: DIPC;DIISOPROPYL CARBONATE;Dissopropyl carbonate;Bis-2-propyl carbonate;Carbonic acid bis(1-methylethyl) ester;Carbonic acid diisopropyl ester;Diisopropyl Carbonate (Stabilized with CalciuM Carbonate)
• CAS NO: 6482-34-4
• Molecular Formula: C₇H₁₄O₃
• Molecular Weight: 146.18
• Mol File: 6482-34-4.mol
• Article Data: 30

Chemical Properties

• Melting Point: <25 °C
• Boiling Point: 147 °C
• Flash Point: 53 °C
• Appearance: /
• Density: 0.945
• Vapor Pressure: 1.39E-07mmHg at 25°C
• Refractive Index: 1.3932
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Ethyl Acetate
• CAS DataBase Reference: Diisopropyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: Diisopropyl carbonate(6482-34-4)
• EPA Substance Registry System: Diisopropyl carbonate(6482-34-4)

Safety Data

• Hazardous Substances Data: 6482-34-4(Hazardous Substances Data)

Usage

Uses

Diisopropyl Carbonate is used in the synthesis of Huperizine A (H826000) a reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for Alzheimer’s disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain.

InChI:InChI=1/C20H26O3/c1-15-6-11-19(18(14-15)20(2,3)4)23-13-12-22-17-9-7-16(21-5)8-10-17/h6-11,14H,12-13H2,1-5H3

Upstream product

• 108-23-6 isopropyl chloroformate 
• 67-63-0 isopropyl alcohol 
• 75-15-0 carbon disulfide 
• 56-23-5 tetrachloromethane 
• 463-71-8 thiophosgene 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 67-56-1 methanol 
• 27108-52-7 isopropyl N-hydroxycarbamate 
• 71-23-8 propan-1-ol 
• 124-38-9 carbon dioxide 
• 75-30-9 2-iodo-propane 
• 24424-99-5 di-tert-butyl dicarbonate 
• 154992-24-2 4-[3-(4-hydroxybutyl)-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile 
• 100-46-9 benzylamine 

Downstream Products

• 89145-28-8 1-methyl-4,5-dihydro-5-(2-fluorophenyl)-2-isopropoxycarbonylaminoimidazole 
• 89145-32-4 1-methyl-4,5-dihydro-5-(2-chlorophenyl)-2-isopropoxycarbonylaminoimidazole 
• 156783-96-9 ethyl 2,2,2-trifluoroethyl carbonate 
• 156783-98-1 methyl (2,2,3,3-tetrafluoropropyl) carbonate 
• 156783-95-8 2,2,2-trifluoroethyl methyl carbonate 
• 72727-72-1 (Z)-2-(hex-3-en-1-yloxy)tetrahydro-2H-pyran 
• 1189537-08-3 (E)-iso-propyl 2-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-pent-2-enoate 
• 1189537-07-2 (E)-iso-propyl 2-ethyl-5-(tetrahydro-2H-pyran-2-yloxy)-pent-2-enoate 
• 26011-68-7 methyl N-(2-phenylethyl)carbamate 
• 63982-24-1 isopropyl N-(2-phenylethyl)carbamate 
• 2453-03-4 trimethylene carbonate 
• 78149-92-5 1,5-Bis-carbamoyloxy-pentan 
• 5440-69-7 N-isopropylbenzamide 
• 103897-19-4 3-benzyltetrahydro-2H-1,3-oxazin-2-one 

Relevant articles and documents

METHOD FOR PRODUCING CARBONATE ESTERS, AND CATALYTIC STRUCTURE FOR PRODUCING CARBONATE ESTERS

Provided are a method for producing carbonate esters, and a catalytic structure for producing carbonate esters, whereby solid catalyst powder formation and detachment are suppressed and superior carbonate ester reaction efficiency is yielded when a catalytic structure constituted by a sufficient quantity of a cerium-oxide-containing solid catalyst supported on a substrate is used. The method for producing carbonate esters includes reacting a monohydric alcohol and carbon dioxide in the presence of a catalytic structure and a hydrating agent. The catalytic structure includes a substrate and a catalytic layer that is formed on at least a portion of the surface of the substrate and contains a solid catalyst and an inorganic binder. The solid catalyst contains cerium oxide. The supported quantity of the solid catalyst is 15 g/m2 to 200 g/m2, inclusive. The inorganic binder contains silica and/or alumina.

Phosgene-free synthesis of symmetric bis(polyfluoroalkyl) carbonates

A phosgene-free synthesis of symmetric bis(polyfluoroalkyl) carbonates involves the transesterification of diphenyl carbonate with polyfluoroalkanols promoted by stoichiometric amounts of titanium(iv) alkoxides.

Method of manufacturing Dialkyl carbonate using carbon dioxide

In the embodiment of the present invention consists of a carbon dioxide using the d alkyl car this [thu [thu] which it sees a manufacturing method is provided other [...] number one, alcohol, imidazolium cation and bicarbonate mixing negative catalyst and bases the solvent to form a mixture, said mixture by mixing said reactants including injecting carbon dioxide for generating an agitating the manufacturing method characterized in that the d alkyl car this [thu [thu] which it sees a number [...] substrate. (by machine translation)