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6498-34-6

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6498-34-6 Usage

General Description

CYCLOHEXYLHYDRAZINE is a chemical compound with the molecular formula C6H13N2. It is a colorless liquid with a slightly ammonia-like odor. CYCLOHEXYLHYDRAZINE is commonly used as a reagent in organic synthesis and as a corrosion inhibitor in steam-generating systems. It is also used in the production of pharmaceuticals and agrochemicals. The compound is considered to be moderately toxic and can cause irritation to the skin, eyes, and respiratory system upon exposure. It is important to handle CYCLOHEXYLHYDRAZINE with caution and follow proper safety guidelines when working with it.

Check Digit Verification of cas no

The CAS Registry Mumber 6498-34-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,9 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6498-34:
(6*6)+(5*4)+(4*9)+(3*8)+(2*3)+(1*4)=126
126 % 10 = 6
So 6498-34-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H14N2/c7-8-6-4-2-1-3-5-6/h6,8H,1-5,7H2

6498-34-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name CYCLOHEXYLHYDRAZINE

1.2 Other means of identification

Product number -
Other names Cyclohexyl-hydrazin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6498-34-6 SDS

6498-34-6Relevant articles and documents

Ogata et al.

, p. 1557 (1966)

Reduction of hydrazines to amines with aqueous solution of titanium(iii) trichloride

Zhang, Yan,Tang, Qiang,Luo, Meiming

supporting information; experimental part, p. 4977 - 4982 (2011/08/05)

N-N bond cleavage in hydrazines is widely used in the preparation of amines and thus occupies a significant place in organic synthesis. In this paper, we report a new method for the reductive cleavage of N-N bonds in hydrazines by commercially available and cheap aqueous titanium(iii) trichloride. The reaction proceeds smoothly under a broad pH range from acidic to neutral and basic conditions to afford amines in good yields. This method is compatible with substrates containing functionalities such as C-C double bonds, benzyl-nitrogen bonds, benzyloxy and acyl groups. The Royal Society of Chemistry 2011.

Pyrazole urea-based inhibitors of p38 MAP kinase: From lead compound to clinical candidate

Regan, John,Moss, Neil,Pargellis, Chris,Pav, Sue,Proto, Alfred,Swinamer, Alan,Tong, Liang,Torcellini, Carol,Breitfelder, Steffen,Cirillo, Pier,Gilmore, Thomas,Graham, Anne G.,Hickey, Eugene,Klaus, Bernhard,Madwed, Jeffrey,Moriak, Monica

, p. 2994 - 3008 (2007/10/03)

We report on a series of N-pyrazole, N′-aryl ureas and their mode of binding to p38 mitogen activated protein kinase. Importantly, a key binding domain that is distinct from the adenosine 5′-triphoshate (ATP) binding site is exposed when the conserved activation loop, consisting in part of Asp168-Phe169-Gly170, adopts a conformation permitting lipophilic and hydrogen bonding interactions between this class of inhibitors and the protein. We describe the correlation of the structure-activity relationships and crystallographic structures of these inhibitors with p38. In addition, we incorporated another binding pharmacophore that forms a hydrogen bond at the ATP binding site. This modification affords significant improvements in binding, cellular, and in vivo potencies resulting in the selection of 45 (BIRB 796) as a clinical candidate for the treatment of inflammatory diseases.

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