65190-89-8

Basic information

• Product Name: 2,6-dimethyl-4-oxo-N,1-diphenyl-1,4-dihydropyridine-3-carboxamide
• Synonyms: 3-pyridinecarboxamide, 1,4-dihydro-2,6-dimethyl-4-oxo-N,1-diphenyl-
• CAS NO: 65190-89-8
• Molecular Formula: C₂₀H₁₈N₂O₂
• Molecular Weight: 318.3691
• Mol File: 65190-89-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 510.2°C at 760 mmHg
• Flash Point: 262.4°C
• Density: 1.237g/cm³
• Vapor Pressure: 1.58E-10mmHg at 25°C
• Refractive Index: 1.647
• CAS DataBase Reference: 2,6-dimethyl-4-oxo-N,1-diphenyl-1,4-dihydropyridine-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-4-oxo-N,1-diphenyl-1,4-dihydropyridine-3-carboxamide(65190-89-8)
• EPA Substance Registry System: 2,6-dimethyl-4-oxo-N,1-diphenyl-1,4-dihydropyridine-3-carboxamide(65190-89-8)

Safety Data

• Hazardous Substances Data: 65190-89-8(Hazardous Substances Data)

Usage

General Description

2,6-dimethyl-4-oxo-N,1-diphenyl-1,4-dihydropyridine-3-carboxamide is a chemical compound with a complex structure. It is a dihydropyridine derivative with two methyl and two phenyl groups attached to the nitrogen and carbon atoms, respectively. The compound possesses a carbonyl group, giving it a ketone functionality. It is commonly used in the pharmaceutical industry as a calcium channel blocker, with potential applications in the treatment of hypertension and angina. Additionally, it may also have potential as a therapeutic agent in the treatment of cardiovascular and neurological diseases. Given its complex structure and potential therapeutic applications, this compound is of interest to researchers and pharmaceutical companies.

Upstream product

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Downstream Products

• 80357-45-5 5-bromo-1,4-dihydro-2,6-dimethyl-N,1-diphenyl-4-oxo-3-pyridinecarboxamide 

Relevant articles and documents

Ni(0)-Cu(i): a powerful combo catalyst for simultaneous coupling and cleavage of the C-N bond with cyclization to valuable amide-based pyrroles and 4-pyridones

Unprecedented ligand-tuned Ni(0)-Cu(i) combo catalysis is demonstrated via sequential bond activated domino C-N/C-C coupled annulation with C-N bond cleavage to afford valuable polysubstituted amide-based pyrroles and 4-pyridones selectively from β-ketoan

Approach to polysubstituted 4-pyridones from N-Aryl acetoacetamides via a N to C 1,3-acyl migration mediated by sodium persulfate

Mediated by sodium persulfate (Na2S2O8), a series of polysubstituted 4-pyridones were synthesized via self-condensation of N-aryl acetoacetamides, during which a novel N to C 1,3-acyl migration should be involved. The stru